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The Molecules of Sperm Exocytosis

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Sperm Acrosome Biogenesis and Function During Fertilization

Part of the book series: Advances in Anatomy, Embryology and Cell Biology ((ADVSANAT,volume 220))

Abstract

Exocytosis is a fundamental process used by eukaryotic cells to release biological compounds and to insert lipids and proteins in the plasma membrane. Specialized secretory cells undergo regulated exocytosis in response to physiological signals. Sperm exocytosis or acrosome reaction (AR) is essentially a regulated secretion with special characteristics. We will focus here on some of these unique features, covering the topology, kinetics, and molecular mechanisms that prepare, drive, and regulate membrane fusion during the AR. Last, we will compare acrosomal release with exocytosis in other model systems.

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Authors and Affiliations

  1. Laboratorio de Biología Celular y Molecular, Instituto de Histología y Embriología, IHEM-CONICET, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, 5500, Mendoza, Mendoza, Argentina

    Silvia A. Belmonte, Luis S. Mayorga & Claudia N. Tomes

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  1. Silvia A. Belmonte
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  2. Luis S. Mayorga
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  3. Claudia N. Tomes
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Correspondence to Claudia N. Tomes .

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  1. Instituto de Biologia y Medicina Experim, Buenos Aires, Argentina

    Mariano G. Buffone

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Belmonte, S.A., Mayorga, L.S., Tomes, C.N. (2016). The Molecules of Sperm Exocytosis. In: Buffone, M. (eds) Sperm Acrosome Biogenesis and Function During Fertilization. Advances in Anatomy, Embryology and Cell Biology, vol 220. Springer, Cham. https://doi.org/10.1007/978-3-319-30567-7_4

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  • DOI: https://doi.org/10.1007/978-3-319-30567-7_4

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