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Late Effects of Treatment and Palliative Care

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Pediatric CNS Tumors

Part of the book series: Pediatric Oncology ((PEDIATRICO))

Abstract

Identifying late effects of treatment and integrating palliative care when appropriate are increasingly recognized as important elements of childhood tumor management. Patients with CNS tumors are at a high risk for mortality, and survivors have high morbidity rates related to the late effects of treatment. While intensified therapy has improved average 5-year survival in patients with pediatric brain tumors to 73 % (Ostrom et al. 2014) from less than 60 % in 1975–1979 (Linabery and Ross 2008), it has also increased the long-term consequences. Survivors may develop a spectrum of late effects ranging from subtle memory loss and cosmetic anomalies to severe neurological disabilities and recurrent neoplasms. While seemingly quite different, both palliative and late-effects care focus on improving quality of life for patients and need to be integrated into the overall care plan.

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Authors and Affiliations

  1. Department of Radiation Oncology, University of California Los Angeles, 200 UCLA Medical Plaza, Suite B265, Los Angeles, CA, 90095-6951, USA

    Eric Chang MD

  2. Division of Hematology/Oncology, Departments of Pediatrics, University of California San Francisco & UCSF Benioff Children’s Hospital, 550 16th St, 4th Floor, 0434, San Francisco, CA, 94143, USA

    Robert Goldsby MD & Anu Banerjee MD

  3. Departments of Neurology, Neurosurgery and Pediatrics, University of California San Francisco & UCSF Benioff Children’s Hospital, 625 Nelson Rising Lane, Room 402C, Sandler Neuroscience Building, San Francisco, CA, 94158, USA

    Sabine Mueller MD, PhD, MAS

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  1. Eric Chang MD
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  2. Robert Goldsby MD
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  3. Sabine Mueller MD, PhD, MAS
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  4. Anu Banerjee MD
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Correspondence to Anu Banerjee MD .

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  1. San Francisco, California, USA

    Nalin Gupta

  2. San Francisco, California, USA

    Anuradha Banerjee

  3. Boston, Massachusetts, USA

    Daphne A. Haas-Kogan

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Chang, E., Goldsby, R., Mueller, S., Banerjee, A. (2017). Late Effects of Treatment and Palliative Care. In: Gupta, N., Banerjee, A., Haas-Kogan, D. (eds) Pediatric CNS Tumors. Pediatric Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-30789-3_17

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