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Cerebral Autoregulation

Part of the book series: SpringerBriefs in Bioengineering ((BRIEFSBIOENG))

Abstract

A key driver for research in cerebral autoregulation is the desire to understand how it is involved in pathophysiological conditions. There is the important question of whether measuring cerebral autoregulation, either at the bedside or during surgery, has clinical value and, if so, how such measurements can be potentially incorporated within decisions about therapy for particular patient groups. It is noticeable how recent studies have investigated a very wide range of clinical pathologies and how much more is known about these in the context of cerebral autoregulation than even just a few years ago. In this chapter, a wide range of clinical contexts will be examined, both ‘normal’ physiological conditions and pathophysiological conditions.

Before beginning, it is worth noting that the clinical context in which autoregulation is considered is still uniformly only one of measurement, rather than treatment, i.e. autoregulation is tested for impairment in different conditions, but it is not directly treated. Autoregulation remains essentially a potential symptom of disease or altered physiology, but it is not one that can directly be adjusted, rather other therapies aim to improve the condition with the potential side benefit being that of improved autoregulation. This will be considered in more detail in the final chapter.

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    Stephen Payne

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Payne, S. (2016). Clinical Conditions. In: Cerebral Autoregulation. SpringerBriefs in Bioengineering. Springer, Cham. https://doi.org/10.1007/978-3-319-31784-7_5

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