Abstract
Prion diseases are uncommon dementias linked to the accumulation in the brain of humans and other mammals of an “infectious” autologous protein. The rapid clinical deterioration of the patients makes them difficult to study with MRS. Their spectroscopic profile includes decreased N-acetylaspartate and increased myo-inositol, reflecting the neuronal loss and gliosis characteristics of these pathologies.
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Galanaud, D. (2016). Magnetic Resonance Spectroscopy in Prion Diseases. In: Öz, G. (eds) Magnetic Resonance Spectroscopy of Degenerative Brain Diseases. Contemporary Clinical Neuroscience. Springer, Cham. https://doi.org/10.1007/978-3-319-33555-1_10
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DOI: https://doi.org/10.1007/978-3-319-33555-1_10
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