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Applications of Microarray Bioprinting

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Microarray Bioprinting Technology

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Abstract

Applications for microarray bioprinting include compound toxicity and efficacy assessments, disease diagnostics, and simulation of tissue microenvironments on a small scale. The low volume, high-throughput nature of this system makes it ideal for rapid screening and assay development, particularly in regards towards assays that can be used on various tissue engineering platforms. In this section, we highlight the development of assays for high-throughput screening (HTS) using microarray bioprinting technologies, with a specific focus on toxicity assays that affect the liver and the central nervous system (CNS). Next, we will highlight the various organ systems that can be recapitulated using 3D bioprinting, and the advantages and disadvantages of tissue miniaturization for microarray technologies. Finally, we’ll discuss other applications, including tissue regeneration studies, and drug patterning.

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  1. Department of Chemical and Biomedical Engineering, Cleveland State University, Washkewicz College of Engineering, Cleveland, OH, USA

    Alexander Roth, Emily Serbinowski & Moo-Yeal Lee

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  1. Alexander Roth
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  1. Department of Chemical and Biomedical Engineering, Cleveland State University, Washkewicz College of Engineering, Cleveland, Ohio, USA

    Moo-Yeal Lee

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Roth, A., Serbinowski, E., Lee, MY. (2016). Applications of Microarray Bioprinting. In: Lee, MY. (eds) Microarray Bioprinting Technology. Springer, Cham. https://doi.org/10.1007/978-3-319-46805-1_8

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