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Biopsychosocial Evaluation of Sexual Dysfunctions

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Abstract

Assessing and treating sexual problems requires an understanding of the biopsychosocial model. This model demonstrates that rarely is there one single factor that will be enough to explain sexual dysfunction in most patients. For effective assessment and treatment it is important to understand the multiple factors that can impact sexual function from the biological or physical, to the psychological, to the religious and sociocultural impacts. This chapter breaks down and summarizes the main components of the biopsychosocial model for assessing sexual dysfunction. It guides the practitioner to the areas that need to be explored to assess and understand the root causes of the sexual dysfunction in patients.

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References

  1. Foley SM. Biopsychosocial assessment and treatment of sexual problems in older age. Curr Sex Health Rep. 2015;7:80–8. doi:10.1007/s11930-015-0047-9.

    Article  Google Scholar 

  2. Balon R, editor. Sexual dysfunction. The brain body connection. Adv Psychsom Med. Vol 29. Basel: Karger; 2008, p. 89–106.

    Google Scholar 

  3. Laumann EO, Paik A, Rosen RC. Sexual dysfunction in the United States prevalence and predictors. JAMA. 1999;281:537–44.

    Article  CAS  PubMed  Google Scholar 

  4. Berry MD, Berry PD. Integrative approaches to the treatment of erectile dysfunction. Curr Sex Health Rep. 2014;6:114–23.

    Article  Google Scholar 

  5. Engel GL. The need for a new medical model: a challenge for biomedicine. Science. 1977;196:129–36.

    Article  CAS  PubMed  Google Scholar 

  6. Engel GL. The clinical application of the biopsychosocial model. Am J Psychiatry. 1980;137:535–44.

    Article  CAS  PubMed  Google Scholar 

  7. Engel GL. From biomedical to biopsychosocial: being scientific in the human domain. Psychosomatics. 1997;38:521–8.

    Article  CAS  PubMed  Google Scholar 

  8. Borrell-Carrió FF. The biopsychosocial model 25 years later: principles, practice, and scientific inquiry. Ann Fam Med. 2004;2(6):576–82.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Brower V. Mind–body research moves towards the mainstream. EMBO Rep. 2006;7(4):358–61.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Borrell-Carrió F, Suchman AL, Epstein RM. The biopsychosocial model 25 years later: principles, practice, and scientific inquiry. Ann Fam Med. 2004;2(6):576–82.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Laumann EO, et al. Sexual problems among women and men aged 40–80 years: prevalence and correlates identified in the global study of sexual attitudes and behaviors. Int J Impot Res. 2005;17(1):39–57.

    Article  CAS  PubMed  Google Scholar 

  12. Maurice WL. Sexual medicine in primary care. St. Louis: Mosby; 1999.

    Google Scholar 

  13. Gottman JM, Silver N. The seven principles for making marriage work: a practical guide from the country’s foremost relationship expert. New York: Random House; 2000.

    Google Scholar 

  14. Gottman JM. Principia amoris: the new science of love. New York: Routledge; 2014.

    Google Scholar 

  15. McCarthy BW, Metz ME. Coping with premature ejaculation: how to overcome PE, please your partner and have great sex. New York: New Harbinger; 2004.

    Google Scholar 

  16. McCarthy BW, Metz ME. Coping with erectile dysfunction: how to regain confidence and enjoy great sex. Oakland, CA: New Harbinger; 2004.

    Google Scholar 

  17. Levine S, Risen CB, Althof SE. Handbook of clinical sexuality for mental health professionals. 2nd ed. NY: Routledge; 2010.

    Google Scholar 

  18. Binik YM, Hall KSK. Principles and practice of sex therapy. 5th ed. New York: Guilford; 2014.

    Google Scholar 

  19. Kleinplatz P. New directions in sex therapy: innovations and alternatives. 2nd ed. New York: Routledge; 2012.

    Google Scholar 

  20. Jean CY, Syrjala KL. Sexuality after hematopoietic stem cell transplantation. Cancer J. 2009;15(1):57.

    Article  Google Scholar 

  21. Laumann EO. Sexual problems among women and men aged 40–80 y: prevalence and correlates identified in the global study of sexual attitudes and behaviors. Int J Impot Res. 2005;17(1):39.

    Article  CAS  PubMed  Google Scholar 

  22. Basson R. The female sexual response: a different model. J Sex Marital Ther. 2000;26(1):51–65.

    Article  CAS  PubMed  Google Scholar 

  23. Basson R. A model of women’s sexual arousal. J Sex Marital Ther. 2002;28(1):1–10.

    Article  PubMed  Google Scholar 

  24. Basson R. Women’s sexual dysfunction: revised and expanded definitions. CMAJ. 2005;172(10):1327–33.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Fisher L. Sex, romance, and relationships: AARP survey of midlife and older adults. AARP. 2010. http://assets.aarp.org/rgcenter/general/srr_09.pdf. Accessed 22 Aug 2016.

  26. DeLamater J. Sexual expression in later life: a review and synthesis. J Sex Res. 2012;49(2–3):125–41.

    Article  PubMed  Google Scholar 

  27. Chao J-K, et al. Relationship among sexual desire, sexual satisfaction, and quality of life in middle-aged and older adults. J Sex Marital Ther. 2011;37(5):386–403.

    Article  PubMed  Google Scholar 

  28. Corona G, et al. Frequency of sexual activity and cardiovascular risk in subjects with erectile dysfunction: cross-sectional and longitudinal analyses. Andrology. 2013;1:864–71.

    Article  CAS  PubMed  Google Scholar 

  29. Foley S, Kope S, Sugrue D. Sex matters for women: a complete guide to taking care of your sexual self. 2nd ed. New York: Guilford; 2012.

    Google Scholar 

  30. Nappi RE, et al. The CLOSER (clarifying vaginal atrophy’s impact on sex and relationships) survey: implications of vaginal discomfort in postmenopausal women and in male partners. J Sex Med. 2013;10(9):2232–41.

    Article  PubMed  Google Scholar 

  31. Kingsberg S, et al. Vulvar and vaginal atrophy in postmenopausal women: findings from the revive (real women’s views of treatment options for menopausal vaginal changes) survey. J Sex Med. 2013;10:1790–9.

    Article  PubMed  Google Scholar 

  32. Parish S, et al. Impact of vulvovaginal health on postmenopausal women: a review of surveys on symptoms of vulvovaginal atrophy. Int J Women’s Health. 2013;13(5):437–47.

    Article  Google Scholar 

  33. Reiter S. Barriers to effective treatment of vaginal atrophy with local estrogen therapy. Int J Gen Med. 2013;6:153–8.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Wang LY, Pierdomenico A, Lefkowitz A, Brandt R. Female sexual health training for oncology providers: new applications. Sex Med. 2015;3(3):189–97.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR. Quality of life in long-term, disease-free survivors of breast cancer: a follow-up study. J Natl Cancer Inst. 2002;94:39–49.

    Article  PubMed  Google Scholar 

  36. Kedde H, Van de Wiel HBM, Schultz WW, Wijsen C. Sexual dysfunction in young women with breast cancer. Support Care Cancer. 2013;21:271–80.

    Article  CAS  PubMed  Google Scholar 

  37. Zebrack BJ, Foley S, Wittmann D, Leonard M. Sexual functioning in young adult survivors of childhood cancer. Psychooncology. 2010;19:814–22.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Davis SR, Panjari M, Robinson PJ, Fradkin P, Bell RJ. Menopausal symptoms in breast cancer survivors nearly 6 years after diagnosis. Menopause. 2014;21:1075–81.

    Article  PubMed  Google Scholar 

  39. Schover LR, Baum GP, Fuson LA, Brewster A, MelhemBertrandt A. Sexual problems during the first 2 years of adjuvant treatment with aromatase inhibitors. J Sex Med. 2014;11:3102–11.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Ussher JM, Perz J, Gilbert E. Information needs associated with changes to sexual well-being after breast cancer. J Adv Nurs. 2013;69:327–37.

    Article  PubMed  Google Scholar 

  41. Hill EK, Sandbo S, Abramsohn E, Makelarski J, Wroblewski K, Wenrich ER, McCoy S, Temkin SM, Yamada SD, Lindau ST. Assessing gynecologic and breast cancer survivors’ sexual health care needs. Cancer. 2011;117:2643–51.

    Article  PubMed  Google Scholar 

  42. Scanlon M, Blaes A, Geller M, Majhail NS, Lindgren B, Haddad T. Patient satisfaction with physician discussions of treatment impact on fertility, menopause and sexual health among pre-menopausal women with cancer. J Cancer. 2012;3:217–25.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Krychman ML, Katz A. Breast cancer and sexuality: multi-modal treatment options (CME). J Sex Med. 2012;9(1):5–13.

    Article  CAS  PubMed  Google Scholar 

  44. Maximizing Sexual Health After Prostate Cancer. Medscape. Nov 13, 2015.

    Google Scholar 

  45. Darwish-Yasine M, Berenji M, Wing D, et al. Evaluating long-term patient centered outcomes following prostate cancer treatment: findings from the Michigan Cancer Survivor study. J Cancer Surviv. 2014;8:121–30.

    Article  Google Scholar 

  46. Sherer BA, Levine LA. Current management of erectile dysfunction in prostate cancer survivors. Curr Opin Urol. 2014;24:401–6.

    Article  PubMed  Google Scholar 

  47. Wittmann D, Skolarus TA, Montie JE. Are we targeting the right outcome for sexual health after prostate cancer treatment? Eur Urol. 2015;68:550–1.

    Article  PubMed  Google Scholar 

  48. Wittmann D. Coping with losses, grief, and mourning in prostate cancer. Adv Psychosom Med. 2015;34:109–22.

    Article  PubMed  Google Scholar 

  49. Wittmann D, Foley S, Balon R. A bisopsyhcosocial approach to sexual recovery after prostate cancer surgery: the role of grief and mourning. J Sex Marital Ther. 2011;37:130–44.

    Article  PubMed  Google Scholar 

  50. Wittmann D, Northouse L, Crossley H, et al. A pilot study of potential pre-operative barriers to couples’ sexual recovery after radical prostatectomy for prostate cancer. J Sex Marital Ther. 2015;41:155–68.

    Article  PubMed  Google Scholar 

  51. Seftel A, Rosen R, Kuritzky L. Physician perceptions of sexual dysfunction related to benign prostatic hyperplasia (BPH) symptoms and sexual side effects related to BPH medications. Int J Impot Res. 2007;19(4):386–92.

    Article  CAS  PubMed  Google Scholar 

  52. Irwig MS, Kolukula S. Persistent sexual side effects of finasteride for male pattern hair loss. J Sex Med. 2011;8(6):1747–53.

    Article  PubMed  Google Scholar 

  53. Maiorino M, Bellastella G, Esposito K. Diabetes and sexual dysfunction: current perspectives. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. March 2014.

    Google Scholar 

  54. Tyrer G, Steel JM, Ewing DJ, Bancroft J, Warner P, Clarke BF. Sexual responsiveness in diabetic women. Diabetologia. 1983;24(3):166–71.

    Article  CAS  PubMed  Google Scholar 

  55. Enzlin P, Mathieu C, Vanderschueren D, Demyttenaere K. Diabetes mellitus and female sexuality: a review of 25 years’ research. Diabet Med. 1998;15(10):809–15.

    Article  CAS  PubMed  Google Scholar 

  56. Gandaglia G. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014;65(5):968.

    Article  PubMed  Google Scholar 

  57. Levine GN. Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation. 2012;125(8):1058.

    Article  PubMed  Google Scholar 

  58. Moser DK, Dracup K, Evangelista LS, Zambroski CH, et al. Comparison of prevalence of symptoms of depression, anxiety, and hostility in elderly patients with heart failure, myocardial infarction, and a coronary artery bypass graft. Heart Lung. 2010;39:378–85.

    Article  PubMed  PubMed Central  Google Scholar 

  59. Roose SP, Seidman SN. Sexual activity and cardiac risk: is depression a contributing factor? Am J Cardiol. 2000;86(2):38–40.

    Article  Google Scholar 

  60. Mosack V, Steinke EE. Trends in sexual concerns after myocardial infarction. J Cardiovasc Nurs. 2009;24:162–70.

    Article  PubMed  Google Scholar 

  61. Lai YH, Hsieh SR, Ho WC, Chiou AF. Factors associated with sexual quality of life in patients before and after coronary artery bypass grafting surgery. J Cardiovasc Nurs. 2011;26:487–96.

    Article  PubMed  Google Scholar 

  62. Phan A, Ishak WW, Shen BJ, Fuess J, et al. Persistent sexual dysfunction impairs quality of life after cardiac transplantation. J Sex Med. 2010;7:2765–73.

    Article  PubMed  Google Scholar 

  63. Kazemi-Saleh D, Pishgou B, Assari S, Tavallaii SA. Fear of sexual intercourse in patients with coronary artery disease: a pilot study of associated morbidity. J Sex Med. 2007;4:1619–25.

    Article  PubMed  Google Scholar 

  64. Wiwanitkit V. Sexuality in Parkinsonism. Sex Disabil. 2008;26:105–8.

    Article  Google Scholar 

  65. Esmail S, Munro B, Gibson N. Couple’s experience with multiple sclerosis in the context of their sexual relationship. Sex Disabil. 2007;25:163–77.

    Article  Google Scholar 

  66. Kool MB, et al. Low relationship satisfaction and high partner involvement predict sexual problems of women with fibromyalgia. Sex Marital Ther. 2006;32(5):409–23.

    Article  Google Scholar 

  67. Binik Y, Hall KS, editors. Principles and practice of sex therapy. 5th ed. New York: Guilford Press; 2014. p. 462.

    Google Scholar 

  68. Tepper M. Sexuality and disability: the missing discourse of pleasure. sexuality and disability. 2000;18(4).

    Google Scholar 

  69. Sipski ML, Alexander CJ, Rosen R. Sexual arousal and orgasm in women: effects of spinal cord injury. Ann Neurol. 2001;49:35–44.

    Article  CAS  PubMed  Google Scholar 

  70. Biering-Sorensen F, Sonksen J. Sexual function in spinal cord lesioned men. Spinal Cord. 2001;39:455–70.

    Article  CAS  PubMed  Google Scholar 

  71. Alexander CJ, Sipski ML, Findley TW. Sexual activities, desire, and satisfaction in males pre- and post-spinal cord injury. Arch Sex Behav. 1993;22:217–28.

    Article  CAS  PubMed  Google Scholar 

  72. Sipski ML, Alexander CJ. Sexual activities, response and satisfaction in women pre- and post-spinal cord injury. Arch Phys Med Rehabil. 1993;74:1025–9.

    Article  CAS  PubMed  Google Scholar 

  73. Taylor Gomez M. The S words: sexuality, sensuality, sexual expression and people with intellectual disability. Sex Disabil. 2012;30(2):237.

    Article  Google Scholar 

  74. Alexander MS, Alexander CJ. Recommendations for discussing sexuality after spinal cord injury/dysfunction in children, adolescents and adults. J Spinal Cord Med. 2007;30:S65–70.

    Article  PubMed  PubMed Central  Google Scholar 

  75. Forsythe E, Horsewell JE. Sexual rehabilitation of women with a spinal cord injury. Spinal Cord. 2006;44:234–41.

    Article  CAS  PubMed  Google Scholar 

  76. Servais L. Sexual health care in persons with intellectual disabilities. Ment Retard Dev Disabil Res Rev. 2006;12:48–56.

    Article  PubMed  Google Scholar 

  77. Eastgate G. Sexual health for people with intellectual disability. Salud Publica Mex. 2008;50(Suppl 2):S255–9.

    Article  PubMed  Google Scholar 

  78. Tarnai B. Review of effective interventions for socially inappropriate masturbation in persons with cognitive disabilities. Sex. Disabil. 2006;24:151–68.

    Article  Google Scholar 

  79. Cuskelly M, Gilmore L. Attitudes to sexuality questionnaire (individuals with an intellectual disability): scale development and community norms. J Intellect Dev Disabil. 2007;32(3):214–21.

    Article  PubMed  Google Scholar 

  80. McVilly KR, et al. Self-advocates have the last say on friendship. Disabil Soc. 2006;21(7):693–708.

    Article  Google Scholar 

  81. Swango-Wilson A. Caregiver perceptions and implications for sex education for individuals with intellectual and developmental disabilities. Sex. Disabil. 2008;26(2):75–81.

    Article  Google Scholar 

  82. Elders MJ. Sex for health and pleasure throughout a lifetime. J Sex Med. 2010;7(Suppl 5):248–9.

    Article  PubMed  Google Scholar 

  83. Noonan A, Taylor Gomez M. Who’s missing? awareness of lesbian, gay, bisexual and transgender people with intellectual disability. Sex. Disabil. 2010;29(2):175–80.

    Article  Google Scholar 

  84. Balon R, editor. Sexual dysfunction. The brain body connection. Adv Psychsom Med. Vol 29. Basel: Karger; 2008. p. 107–30.

    Google Scholar 

  85. Manolis A. Antihypertensive treatment and sexual dysfunction. Curr Hypertens Rep. 2012;14(4):285.

    Article  CAS  PubMed  Google Scholar 

  86. Balon R, editor. Sexual dysfunction. The brain body connection. Adv Psychsom Med. Vol 29. Basel: Karger; 2008. p. 131–49.

    Google Scholar 

  87. Casper RC, Redmond DE, Katz MM, Schaffer CB, Davis JM, Doslow SH. Somatic symptoms in primary affective disorder. Arch Gen Psychiatry. 1985;42:1098–104.

    Article  CAS  PubMed  Google Scholar 

  88. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol. 1994;151:54–61.

    CAS  PubMed  Google Scholar 

  89. Waldinger MD. Lifelong premature ejaculation: from authority-based to evidence-based medicine. BJU Int. 2004;93:201.

    Article  CAS  PubMed  Google Scholar 

  90. McMahon CG, Abdo C, Incrocci L, Perelman M, Rowland D, Waldinger M, Xin ZC. Disorders of orgasm and ejaculation in men. J Sex Med. 2004;1(1):58–65.

    Article  PubMed  Google Scholar 

  91. Waldinger MD. The neurobiological approach to premature ejaculation. J Urol. 2002;168:2359.

    Article  PubMed  Google Scholar 

  92. Althof SE. Original research—psychology: psychological and interpersonal dimensions of sexual function and dysfunction. J Sex Med. 2005;2(6):793.

    Article  PubMed  Google Scholar 

  93. Maggi M, Filippi S, Ledda F, et al. Erectile dysfunction: from biochemical pharmacology to advances in medical therapy. Eur J Endocrinol. 2000;143:143–54.

    Article  CAS  PubMed  Google Scholar 

  94. Filippi S, Marini M, Vannelli GB, et al. Effects of hypoxia on endothelin-1 sensitivity in the corpus cavernosum. Mol Hum Reprod. 2003;9:765–74.

    Article  CAS  PubMed  Google Scholar 

  95. Corretti G, Baldi I. The relationship between anxiety disorders and sexual dysfunction. Psychiatr Times. 2007;24(9):16–21.

    Google Scholar 

  96. Carvalho J. Biopsychosocial determinants of men’s sexual desire: testing an integrative model. J Sex Med. 2011;8(3):754.

    Article  PubMed  Google Scholar 

  97. Beck JG, Barlow DH, Sakheim DK, Abrahamson DJ. Shock threat and sexual arousal: the role of selective attention, thought content and affective states. Psychophysiology. 1987;24:165–72.

    Article  CAS  PubMed  Google Scholar 

  98. Geer JH, Fuhr R. Cognitive factors in sexual arousal: the role of distraction. J Consult Clin Psychol. 1976;44:238–43.

    Article  CAS  PubMed  Google Scholar 

  99. Dove NL, Wiederman MW. Cognitive distraction and women’s sexual functioning. J Sex Marital Ther. 2000;26:67–78.

    Article  CAS  PubMed  Google Scholar 

  100. Elliot AN, O’Donohue WT. The effects of anxiety and distraction on sexual arousal in a non-clinical sample of heterosexual women. Arch Sex Behav. 1997;26:607–24.

    Article  Google Scholar 

  101. Attalah S, Johnson-Agbakwu C, Rosenbaum T, et al. Ethical and sociocultural aspects of sexual function and dysfunction in both sexes. J Sex Med. 2016;13:591e606.

    Google Scholar 

  102. Sue D, Arredondo P, RJ MD. Multicultural counseling competencies and standards: a call to the profession. J Couns Dev. 1992;70(4):477–86.

    Article  Google Scholar 

  103. Lu FG, Lim RF, Mezzich JE. Issues in the assessment and diagnosis of culturally diverse individuals. Am Psychiatr Press Rev Psychiatr. 1995.

    Google Scholar 

  104. Cardemil E, Battle C. Guess who’s coming to therapy? Getting comfortable with conversations about race and ethnicity in psychotherapy. Prof Psychol Res Pract. 2003;34:278–86.

    Article  Google Scholar 

  105. Kellogg SS, Rosenbaum TY, Dweck A, Millheiser L, PillaiFriedman S, Krychman M, et al. Sexual health and religion: a primer for the sexual health clinician. J Sex Med. 2014;11:1606–19.

    Article  Google Scholar 

  106. Atallah S, Johnson-Agbakwu C, Rosenbaum T, et al. Ethical and sociocultural aspects of sexual function and dysfunction in both sexes. J Sex Med. 2016;13(4):591–606.

    Article  PubMed  Google Scholar 

  107. Herman J. Trauma and recovery: the aftermath of violence–from domestic abuse to political terror. New York: Basic Books; 1997.

    Google Scholar 

  108. Tiefer L. A new view of women’s sexual problems: why new? why now? J Sex Res. 2001;38(2):89.

    Article  Google Scholar 

  109. Kramarae C, Spender D (Eds). The knowledge explosion: generations of feminist scholarship. New York: Columbia University Teachers College Press; 1992.

    Google Scholar 

  110. Cole E, Rothblum ED (Eds). Women and sex therapy. New York: Haworth Press; 1988.

    Google Scholar 

  111. Tiefer L, Melman A. Interview of wives: a necessary adjunct in the evaluation of impotence. Sex Disabil. 1983;6:167–75.

    Article  Google Scholar 

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Pahwa, P.K., Foley, S.M. (2017). Biopsychosocial Evaluation of Sexual Dysfunctions. In: IsHak, W. (eds) The Textbook of Clinical Sexual Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-52539-6_6

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