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Technical Aspects for the Evaluation of Circulating Tumor Cells (CTCs)

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Liquid Biopsy in Cancer Patients

Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

Liquid biopsy is considered a valid strategy to improve patients’ selection and treatment monitoring in clinical practice. Indeed Circulating Tumor Cells (CTCs) represent an important component of liquid biopsy and their clinical evaluation is becoming fundamental for a better patients’ stratification. Several techniques have been developed for CTCs isolation and enrichment and in this chapter we provide an updated overview of the main strategies that can be used.

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Author information

Authors and Affiliations

  1. Department of Surgical, Oncogical and Oral Sciences, Section of Medical Oncology, University of Palermo, Via del Vespro 127, Palermo, 90127, Italy

    A. B. Di Stefano & M. Castiglia

  2. Section of Clinical Biochemistry and Clinical Molecular Medicine, Department of Biopathology and Medical Biotechnology, University of Palermo – U.O.C. Laboratory Medicine – CoreLab, Policlinico University Hospital, Palermo, Italy

    M. Ciaccio

  3. Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy

    Viviana Bazan

Authors
  1. A. B. Di Stefano
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  2. M. Castiglia
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  3. M. Ciaccio
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  4. Viviana Bazan
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Corresponding author

Correspondence to Viviana Bazan .

Editor information

Editors and Affiliations

  1. College of Science and Technology, Temple University Sbarro Institute for Cancer Research, Philadelphia, Pennsylvania, USA

    Antonio Russo

  2. Surgical and Oncological Sciences, University of Palermo School of Medicine, Palermo, Italy

    Antonio Giordano

  3. Oncology, University Hospital Antwerp, Edegem, Antwerpen, Belgium

    Christian Rolfo

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© 2017 Springer International Publishing AG

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Di Stefano, A.B., Castiglia, M., Ciaccio, M., Bazan, V. (2017). Technical Aspects for the Evaluation of Circulating Tumor Cells (CTCs). In: Russo, A., Giordano, A., Rolfo, C. (eds) Liquid Biopsy in Cancer Patients. Current Clinical Pathology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-55661-1_5

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  • DOI: https://doi.org/10.1007/978-3-319-55661-1_5

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-55659-8

  • Online ISBN: 978-3-319-55661-1

  • eBook Packages: MedicineMedicine (R0)

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