Skip to main content

Is Crowdsourcing Patient-Reported Outcomes the Future of Evidence-Based Medicine? A Case Study of Back Pain

  • Conference paper
  • First Online:
Artificial Intelligence in Medicine (AIME 2017)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 10259))

Included in the following conference series:

Abstract

Evidence is lacking for patient-reported effectiveness of treatments for most medical conditions and specifically for lower back pain. In this paper, we examined a consumer-based social network that collects patients’ treatment ratings as a potential source of evidence. Acknowledging the potential biases of this data set, we used propensity score matching and generalized linear regression to account for confounding variables. To evaluate validity, we compared results obtained by analyzing the patient reported data to results of evidence-based studies. Overall, there was agreement on the relationship between back pain and being obese. In addition, there was agreement about which treatments were effective or had no benefit. The patients’ ratings also point to new evidence that postural modification treatment is effective and that surgery is harmful to a large proportion of patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Hoy, D., Bain, C., William, G., March, L., Brooks, P., Blyth, F., et al.: A systematic review of the global prevalence of low back pain. Arthritis Rheum. 64, 2028–2037 (2012)

    Article  Google Scholar 

  2. Chou, R., Deyo, R.A., Jarvik, J.G.: Appropriate use of lumbar imaging for evaluation of low back pain. Radiol. Clin. North Am. 50, 569–585 (2012)

    Article  Google Scholar 

  3. Deyo, R.A., Dworkin, S.F., Amtmann, D., et al.: Report of the NIH task force on research standards for chronic low back pain. Int. J. Ther. Massage Bodyw. 8(3), 16–33 (2015)

    Google Scholar 

  4. Hersh, W.R., Weiner, M.G., Embi, P.J., et al.: Caveats for the use of operational electronic health record data in comparative effectiveness research. Med. Care 5, S30–S37 (2014)

    Google Scholar 

  5. Tannen, R.L., Weiner, M.G., Xie, D.: Use of primary care electronic medical record database in drug efficacy research on cardiovascular outcomes: comparison of database and randomised controlled trial findings. Br. Med. J. 338, b81 (2009)

    Article  Google Scholar 

  6. Tatonett, N.P., Ye, P.P., Daneshjou, R., Altman, R.B.: Data-driven prediction of drug effects and interactions. Sci. Trans. Med. 4(125), 1–26 (2013)

    Google Scholar 

  7. Harpaz, R., DuMouchel, W., Shah, N.H., et al.: Novel data mining methodologies for adverse drug event discovery and analysis. Clin. Pharmacol. Ther. 91(6), 1010–1021 (2012)

    Article  Google Scholar 

  8. Bhandari, R.P., Feinstein, A.B., Huestis, S.E., et al.: Pediatric-collaborative health outcomes information registry (Peds-CHOIR): a learning health system to guide pediatric pain research and treatment. Pain 157(9), 2033–2044 (2016)

    Article  Google Scholar 

  9. Bove, R., Secor, E., Healy, B., et al.: Evaluation of an online platform for multiple sclerosis research: patient description, validation of severity scale, and exploration of BMI effects on disease course. PLoS ONE 8(3), e59707 (2013)

    Article  Google Scholar 

  10. Nakamura, C., Bromberg, M., Bhargava, S., et al.: Mining online social network data for biomedical research: a comparison of clinicians’ and patients’ perceptions about amyotrophic lateral sclerosis treatments. J. Med. Internet Res. 14(3), e90 (2012)

    Article  Google Scholar 

  11. Peleg, M.: Appendices (2017). http://mis.haifa.ac.il/~morpeleg/PatientOutcomesAppend.html

  12. Morone, N.E., Greco, C.M., Moore, C.G., et al.: A mind-body program for older adults with chronic low back pain: a randomized clinical trial. JAMA Int. Med. 3, 329–337 (2016)

    Article  Google Scholar 

  13. Heuch, I., Hagen, K., Heuch, I., et al.: The impact of body mass index on the prevalence of low back pain: the HUNT study. Spine (Phila Pa 1976) 35(7), 764–768 (2010)

    Article  Google Scholar 

  14. Chou, R., Huffman, L.H.: Nonpharmacologic therapies for acute and chronic low back pain: a review of the evidence for an American Pain Soc. Ann. Int. Med. 147, 492–504 (2007)

    Article  Google Scholar 

  15. Chou, R., Atlas, S.J., Stanos, S.P., Rosenquist, R.W.: Nonsurgical interventional therapies for low back pain: a review of the evidence for an American Pain Soc. Spine 34, 1078–1093 (2009)

    Article  Google Scholar 

  16. Chou, R., Huffman, L.H.: Medications for acute and chronic low back pain: a review of the evidence for an American Pain Soc. Ann. Intern. Med. 147, 505–514 (2007)

    Article  Google Scholar 

  17. Institute for Clinical Systems Improvement. Adult Acute and Subacute Low Back Pain, November 2012

    Google Scholar 

  18. Biondi-Zoccai, G., Romagnol, E., Agostoni, P., et al.: Are propensity scores really superior to standard multivariable analysis? Contemp. Clin. Trials. 32(5), 731–740 (2011)

    Article  Google Scholar 

  19. Wang, Y.C., Burke, M., Kraut, R.E.: Gender, topic, and audience response: an analysis of user-generated content on facebook. In: SIGCHI Conference on Human Factors in Computing Systems, pp. 31–34 (2013)

    Google Scholar 

Download references

Acknowledgement

We thank Ofer Ben-Shachar for supplying the HealthOutcome data and thank him and Tobias Konitzer for the valuable discussions.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mor Peleg .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Peleg, M., Leung, T.I., Desai, M., Dumontier, M. (2017). Is Crowdsourcing Patient-Reported Outcomes the Future of Evidence-Based Medicine? A Case Study of Back Pain. In: ten Teije, A., Popow, C., Holmes, J., Sacchi, L. (eds) Artificial Intelligence in Medicine. AIME 2017. Lecture Notes in Computer Science(), vol 10259. Springer, Cham. https://doi.org/10.1007/978-3-319-59758-4_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-59758-4_27

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59757-7

  • Online ISBN: 978-3-319-59758-4

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics