Abstract
The trigeminal nerve block or neurolysis through the foramen ovale approach is used in the diagnosis and treatment of trigeminal neuralgia, which is a chronic neuropathic facial pain syndrome affecting millions of people worldwide. Idiopathic trigeminal neuralgia is primarily due to demyelination of trigeminal sensory fibers within either the nerve root or the brainstem. It is diagnosed based on typical signs and symptoms and exclusion of other causes of facial pain. Characteristic clinical presentation includes unilateral lancinating pain, paroxysmal attacks following neural disturbance, and a refractory period. The trigeminal nerve blocks and neurolysis are indicated in patients who have failed to respond to conservative treatments with medications. There are three procedures (radiofrequency thermocoagulation, balloon compression, and glycerolysis) that target the Gasserian ganglion and several procedures that target the branches of the trigeminal nerve. The neurodestructive procedures may produce long-term pain relief but can also cause numbness and dysesthesia in specific areas of trigeminal nerve innervation. Pulsed radiofrequency is a non-neurodestructive option but its efficacy is not as remarkable. Various treatment options should be weighed in risks and benefits, and the patients should be included in the decision-making process.
References
Katusic S, Beard CM, Bergstralh E, et al. Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945-1984. Ann Neurol. 1990;27:89–95.
Fothergill J. Of a painful affection of the face. In: Medical observations and inquiries by a society of physicians in London. London: Society of Physicians; 1776. p. 129–42.
Prasad S, Galetta S. Trigeminal neuralgia: historical notes and current concepts. Neurologist. 2009;15:87–94.
Hartel F. Die Leitungsanesthesie und Injektionsbehandlung des Ganglion Gasseri und der Trigeminusaeste. Arch Klin Chir. 1912;100:193–292.
Kirschner M. Zur Electrochirurgie. Arch Klin Chir. 1931;161:761–8.
Putnam TJ, Hamptom AO. A technique of injection into the gasserian ganglion under roentgenographic control. Arch Neurol Psychiatr. 1936;35:92–8.
Jannetta PJ. Microsurgical approach to the trigeminal nerve for tic douloureux. Prog Neurosurg. 1976;7:180–200.
Sweet WH, Wepsic JG. Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction of pain fibers. 1. Trigeminal neuralgia. J Neurosurg. 1974;40:143–56.
Håkanson S. Trigeminal neuralgia treated by the injection of glycerol into the trigeminal cistern. Neurosurgery. 1981;9:638–46.
Mullan S, Lichtor T. Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. J Neurosurg. 1983;59:1007–12.
Love S, Coakham HB. Trigeminal neuralgia: pathology and pathogenesis. Brain. 2001;124:2347–60.
Barker FG II, Jannetta PJ, Bissonette DJ, et al. The long-term outcome of microvascular decompression for trigeminal neuralgia. N Engl J Med. 1996;334:1077–83.
Yoshino N, Akimoto H, Yamada I, et al. Trigeminal neuralgia: evaluation of neuralgic manifestation and site of neurovascular compression with 3D CISS MR imaging and MR angiography. Radiology. 2003;228:539–45.
Jannetta PJ. Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia. J Neurosurg. 1967;26:S159–62.
Hilton DA, Love S, Gradidge T, et al. Pathological findings associated with trigeminal neuralgia caused by vascular compression. Neurosurgery. 1994;35:299–303.
Watson JC. From paroxysmal to chronic pain in trigeminal neuralgia: implications of central sensitization. Neurology. 2007;69:817–8.
Smith KJ, McDonald WI. Spontaneous and mechanically evoked activity due to central demyelinating lesion. Nature. 1980;286:154–5.
Edlich RF, Winters KL, Britt L, et al. Trigeminal neuralgia. J Long-Term Eff Med Implants. 2006;16:185–92.
Jensen TS, Rasmussen P, Reske-Nielsen E. Association of trigeminal neuralgia with multiple sclerosis: clinical and pathological features. Acta Neurol Scand. 1982;65:182–9.
Chong VF. Trigeminal neuralgia in nasopharyngeal carcinoma. J Laryngol Otol. 1996;110:394–6.
Bornemann A, Bohl J, Hey O, et al. Amyloidoma of the gasserian ganglion as a cause of symptomatic neuralgia of the trigeminal nerve: report of three cases. J Neurol. 1993;241:10–4.
Coffey RJ, Fromm GH. Familial trigeminal neuralgia and Charcot-Marie-tooth neuropathy. Report of two families and review. Surg Neurol. 1991;35:49–53.
Headache Classification Subcommittee of the International Headache Society. The International classification of headache disorders. 2nd edition. Cephalalgia. 2004;24:S126–36.
Zakrzewska JM. Diagnosis and differential diagnosis of trigeminal neuralgia. Clin J Pain. 2002;18:14–21.
Cohen AS, Matharu MS, Goadsby PJ. SUNCT syndrome in the elderly. Cephalalgia. 2004;24:508–9.
Burchiel K, Steege T, Howe JF, et al. Comparison of percutaneous radiofrequency gangliolysis and microvascular decompression for the surgical management of tic douloureux. Neurosurgery. 1981;9:111–9.
North RB, Kidd DH, Piantadosi S, et al. Percutaneous retrogasserian glycerol rhizotomy: predictors of success and failure in treatment of trigeminal neuralgia. J Neurosurg. 1990;72:851–6.
Apfelbaum RI. Comparison of the long-term results of microvascular decompression and percutaneous trigeminal neurolysis for the treatment of trigeminal neuralgia. International Congress Series, Volume 1247, December 2002, pp. 629–643. Developments in Neuroscience. In: Proceedings of the 2nd International Mt. Bandai Symposium for Neuroscience, Bandai, Japan, October 27, 2001.
Chua NH, Halim W, Beems T, et al. Pulsed radiofrequency treatment for trigeminal neuralgia. Anesth Pain Med. 2012;1:257–61.
Zakrzewska JM. Trigeminal neuralgia. In: Zakrzewska JM, Harrison SD, editors. Assessment and management of orofacial pain. Pain research and clinical management, vol. 14. Amsterdam: Elsevier; 2002. p. 267–370.
Day M. Neurolysis of the trigeminal and sphenopalatine ganglions. Pain Pract. 2001;1:171–82.
Brown DL. Atlas of regional anesthesia. 4th ed. Philadelphia: Saunders; 2010. p. 151–70.
Raj PP. Interventional pain management: image guided procedures. Philadelphia: Saunders; 2008.
Sluijter M, van Kleef M. Characteristics and mode of action of radiofrequency lesioning. Curr Rev Pain. 1998;2:143–50.
Wedel DJ, Horlocker TT. Nerve blocks. Chapter 52. In: Miller’s anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2009.
Tsui BC. Ultrasound imaging to localize foramina for superficial trigeminal nerve block. Can J Anaesth. 2009;56:704–6.
Taha JM, Tew JM. Comparison of surgical treatments for trigeminal neuralgia: reevaluation of radiofrequency rhizotomy. Neurosurgery. 1966;38:865–71.
Sweet WH. Complications of treating trigeminal neuralgia: an analysis of the literature and response to questionnaire. In: Rovit RL, Murali R, Jannetta PJ, editors. Trigeminal Neuralgia. Baltimore: Williams & Wilkins; 1990. p. 251–79.
Sekhar LN, Heros RG, Kerber CW. Carotid-cavernous fistula following percutaneous retrogasserian procedures. J Neurosurg. 1979;51:700–6.
Rish BL. Cerebrovascular accident after percutaneous radiofrequency thermocoagulation of the trigeminal ganglion. J Neurosurg. 1976;44:376–7.
Sweet WH, Poletti CE, Roberts JT. Dangerous rises in blood pressure upon heating of trigeminal rootlets: increased bleeding time in patients with trigeminal neuralgia. Neurosurgery. 1985;17:843–4.
Wallace MS, Staats PS. Pain medicine and management: just the facts. New York City: McGraw-Hill; 2005.
Manchikanti L, Kaye AD, Falco FJE. Antithrombotic and antiplatelet therapy. In: Manchikanti L, Kaye AD, Falco FJE, et al., editors. Essentials of interventional techniques in managing chronic pain. Berlin: Springer; 2017.
Manchikanti L, Falco FJE, Benyamin RM, et al. Assessment of bleeding risk of interventional techniques: a best evidence synthesis of practice patterns and perioperative management of anticoagulant and antithrombotic therapy. Pain Physician. 2013;16:SE261–318.
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(Sean) Lin, CS., Cheng, J. (2018). Trigeminal Nerve Blocks and Neurolysis. In: Manchikanti, L., Kaye, A., Falco, F., Hirsch, J. (eds) Essentials of Interventional Techniques in Managing Chronic Pain. Springer, Cham. https://doi.org/10.1007/978-3-319-60361-2_26
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