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Type 2 Diabetes

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Diabetes in Pregnancy
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Abstract

This chapter reviews the epidemiology, genetics, and pathophysiology of type 2 diabetes. Topics covered include insulin resistance, obesity and β-cell dysfunction, complications of type 2 diabetes during pregnancy, prediabetes, prevention of type 2 diabetes, and diagnosis and management of type 2 diabetes during pregnancy.

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References

  1. Dunne F, Brydon P, Smith K, Gee H. Pregnancy in women with Type 2 diabetes: 12 years outcome data 1990–2002. Diabet Med. 2003;20(9):734–8.

    Article  CAS  PubMed  Google Scholar 

  2. Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet. 2011;378(9786):169–81. doi:10.1016/S0140-6736(11)60614-4.

    Article  PubMed  Google Scholar 

  3. Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet. 2005;365(9467):1333–46. doi:10.1016/S0140-6736(05)61032-X.

    Article  CAS  PubMed  Google Scholar 

  4. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33(Suppl 1):S62–9. doi:10.2337/dc10-S062.

    Article  PubMed Central  Google Scholar 

  5. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 1997;20(7):1183–97.

    Article  Google Scholar 

  6. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2003;26(Suppl 1):S5–20.

    Google Scholar 

  7. Gunderson EP, Hedderson MM, Chiang V, Crites Y, Walton D, Azevedo RA, Fox G, Elmasian C, Young S, Salvador N, Lum M, Quesenberry CP, Lo JC, Sternfeld B, Ferrara A, Selby JV. Lactation intensity and postpartum maternal glucose tolerance and insulin resistance in women with recent GDM: the SWIFT cohort. Diabetes Care. 2012;35(1):50–6. doi:10.2337/dc11-1409.

    Article  CAS  PubMed  Google Scholar 

  8. Gunderson EP, Jacobs DR Jr, Chiang V, Lewis CE, Feng J, Quesenberry CP Jr, Sidney S. Duration of lactation and incidence of the metabolic syndrome in women of reproductive age according to gestational diabetes mellitus status: a 20-year prospective study in CARDIA (coronary artery risk development in young adults). Diabetes. 2010;59(2):495–504. doi:10.2337/db09-1197.

    Article  CAS  PubMed  Google Scholar 

  9. Stuebe AM, Kleinman K, Gillman MW, Rifas-Shiman SL, Gunderson EP, Rich-Edwards J. Duration of lactation and maternal metabolism at 3 years postpartum. J Women’s Health. 2010;19(5):941–50. doi:10.1089/jwh.2009.1660.

    Article  Google Scholar 

  10. Hod M, Hadar E, Cabero-Roura L. Prevention of type 2 diabetes among women with prior gestational diabetes mellitus. Int J Gynaecol Obstet. 2015;131(Suppl 1):S16–8. doi:10.1016/j.ijgo.2015.02.010.

    Article  PubMed  Google Scholar 

  11. Ratner RE, Christophi CA, Metzger BE, Dabelea D, Bennett PH, Pi-Sunyer X, Fowler S, Kahn SE, The Diabetes Prevention Program Research Group. Prevention of diabetes in women with a history of gestational diabetes: effects of metformin and lifestyle interventions. J Clin Endocrinol Metab. 2008;93(12):4774–9. doi:10.1210/jc.2008-0772.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M, Group S-NTR. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet. 2002;359(9323):2072–7. doi:10.1016/S0140-6736(02)08905-5.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Lisa E. Moore MD, FACOG .

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© 2018 Springer International Publishing AG

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Moore, L.E. (2018). Type 2 Diabetes. In: Moore, L. (eds) Diabetes in Pregnancy. Springer, Cham. https://doi.org/10.1007/978-3-319-65518-5_5

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  • DOI: https://doi.org/10.1007/978-3-319-65518-5_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-65517-8

  • Online ISBN: 978-3-319-65518-5

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