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Endocrine Disruptors as Obesogens

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Pediatric Obesity

Part of the book series: Contemporary Endocrinology ((COE))

Abstract

Substantial effort has been devoted to explaining secular trends in childhood obesity and metabolic risks to unhealthy diet and physical activity. While some studies have suggested these factors may play a role in the obesity epidemic, even these studies have only been able to conclude that these factors have a moderate role. Given that a single-generation transformation in the human genome is even more unlikely to have transformed susceptibility to excess weight gain in early life, we are left with the reality that environmental influences represent important risks for obesity and dysmetabolism. In contrast to diet and physical activity, which can require intensive attention, effort and costs to modify through behavioral and other interventions, government action can fundamentally transform the environment and prevent disease and disability. The costs of regulations to limit environmental obesogens can also be much lower than the benefits to society.

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Authors and Affiliations

  1. Department of Pediatrics, Environmental Medicine, and Population Health, New York University School of Medicine, New York, NY, USA

    Leonardo Trasande MD, MPP

  2. Department of Developmental and Cell Biology, Department of Pharmaceutical Sciences, Department of Biomedical Engineering, University of California at Irvine, Irvine, CA, USA

    Bruce Blumberg PhD

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  1. Leonardo Trasande MD, MPP
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  2. Bruce Blumberg PhD
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Correspondence to Leonardo Trasande MD, MPP .

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  1. Duke University School of Medicine , Durham, North Carolina, USA

    Michael S. Freemark

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Trasande, L., Blumberg, B. (2018). Endocrine Disruptors as Obesogens. In: Freemark, M. (eds) Pediatric Obesity. Contemporary Endocrinology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-68192-4_14

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  • DOI: https://doi.org/10.1007/978-3-319-68192-4_14

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