Skip to main content
SpringerLink
Log in

Venous Thromboembolism: Deep Venous Thrombosis and Pulmonary Embolism

  • Chapter
  • First Online:
IR Playbook

  • 2790 Accesses

Abstract

Venous thromboembolism (VTE) is the third most life-threatening cardiovascular disease in the USA, affecting a significant number of people each year. The treatment of VTE, encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), includes both medical and interventional therapies. The severity of the disease varies, with some patients requiring only outpatient medical management, while others may experience significant lifelong morbidity, limb loss, or death. This chapter discusses the pathophysiology of VTE and its historical origins and treatments. Clinical manifestations, diagnostic and treatment methods, and procedural techniques are reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Goodman LR. Search of venous thromboembolism: the first 2913 years. AJR Am J Roentgenol. 2013;201(4):W576–81.

    Article  PubMed  Google Scholar 

  2. Hume M. Pulmonary embolism. Historical aspects. Arch Surg. 1963;87:709–14.

    Article  CAS  PubMed  Google Scholar 

  3. Virchow R. Weitere Untersuchungen ueber die Verstopfung der Lungenarterien und ihre Folge. Traube’ s Beitraege exp Path u. Physiol. 1846;2:21–31.

    Google Scholar 

  4. Galanaud JP, Laroche JP, Righini M. The history and historical treatments of deep vein thrombosis. J Thromb Haemost. 2013;11(3):402–11.

    Article  CAS  PubMed  Google Scholar 

  5. Wilbur J, Shian B. Deep venous thrombosis and pulmonary embolism: current therapy. Am Fam Physician. 2017;95(5):295–302.

    PubMed  Google Scholar 

  6. Savader SJ, Gomez-Jorge J. Peripheral and central deep venous thrombosis. In: Savader SJ, et al., editors. Venous interventional radiology with clinical perspectives. 2nd ed. New York: Thieme; 2000.

    Google Scholar 

  7. Kroegel C, Reissig A. Principle mechanisms underlying venous thromboembolism: epidemiology, risk factors, pathophysiology and pathogenesis. Respiration. 2003;70(1):7–30.

    Article  PubMed  Google Scholar 

  8. Turpie AG, Chin BS, Lip GY. Venous thromboembolism: pathophysiology, clinical features, and prevention. BMJ. 2002;325(7369):887–90.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Johnson M. Pulmonary embolism: diagnosis and interventional options for treatment. In: Savader SJ, et al., editors. Venous interventional radiology with clinical perspectives. 2nd ed. New York: Thieme; 2000.

    Google Scholar 

  10. Vedantham S. Interventional approaches to deep vein thrombosis. Am J Hematol. 2012;87(Suppl 1):S113–8.

    Article  PubMed  Google Scholar 

  11. Bates SM, Ginsberg JS. Clinical practice. Treatment of deep-vein thrombosis. N Engl J Med. 2004;351(3):268–77.

    Article  CAS  PubMed  Google Scholar 

  12. Kearon C, Akl EA, Ornelas J, Blaivas A, Jimenez D, Bounameaux H, et al. Antithrombotic therapy for VTE disease. Chest. 2016;149(2):315–52.

    Article  PubMed  Google Scholar 

  13. Lee AY, Levine MN, Baker RI, Bowden C, Kakkar AK, Prins M, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med. 2003;349(2):146–53.

    Article  CAS  PubMed  Google Scholar 

  14. Group PS. Eight-year follow-up of patients with permanent vena cava filters in the prevention of pulmonary embolism: the PREPIC (prevention du Risque d’Embolie Pulmonaire par interruption cave) randomized study. Circulation. 2005;112(3):416–22.

    Article  Google Scholar 

  15. Vedantham S. Treating infrainguinal deep venous thrombosis. Tech Vasc Interv Radiol. 2014;17(2):103–8.

    Article  PubMed Central  PubMed  Google Scholar 

  16. Dudzinski DM, Piazza G. Multidisciplinary pulmonary embolism response teams. Circulation. 2016;133(1):98–103.

    Article  PubMed  Google Scholar 

  17. Aujesky D, Obrosky DS, Stone RA, Auble TE, Perrier A, Cornuz J, et al. Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med. 2005;172(8):1041–6.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galie N, et al. ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J. 2014;35(43):3033–69. 69a-69k

    Article  CAS  PubMed  Google Scholar 

  19. Konstantinides S, Tiede N, Geibel A, Olschewski M. Just H, Kasper W. Comparison of alteplase versus heparin for resolution of major pulmonary embolism. Am J Cardiol. 1998;82(8):966–70.

    Article  CAS  PubMed  Google Scholar 

  20. Amin VB, Lookstein RA. Catheter-directed interventions for acute iliocaval deep vein thrombosis. Tech Vasc Interv Radiol. 2014;17(2):96–102.

    Article  PubMed  Google Scholar 

  21. Garcia MJ, Lookstein R, Malhotra R, Amin A, Blitz LR, Leung DA, et al. Endovascular Management of Deep Vein Thrombosis with Rheolytic Thrombectomy: final report of the prospective multicenter PEARL (peripheral use of AngioJet Rheolytic Thrombectomy with a variety of catheter lengths) registry. J Vasc Interv Radiol. 2015 June;26(6):777–85.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, NYU Langone Medical Center, New York, NY, USA

    Arya F. Derakhshani

  2. Department of Radiology/Vascular and Interventional Radiology, NYU Langone Medical Center, New York, NY, USA

    Amish Patel & Akhilesh Sista

Authors
  1. Arya F. Derakhshani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Amish Patel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Akhilesh Sista
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Akhilesh Sista .

Editor information

Editors and Affiliations

  1. Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA

    Nicole A. Keefe

  2. Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA

    Ziv J Haskal

  3. Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA

    Auh Whan Park

  4. Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA

    John F. Angle

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Derakhshani, A.F., Patel, A., Sista, A. (2018). Venous Thromboembolism: Deep Venous Thrombosis and Pulmonary Embolism. In: Keefe, N., Haskal, Z., Park, A., Angle, J. (eds) IR Playbook. Springer, Cham. https://doi.org/10.1007/978-3-319-71300-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-71300-7_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-71299-4

  • Online ISBN: 978-3-319-71300-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation