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Standards for Conducting Ophthalmic Examinations in Laboratory Animals

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Standards for Ocular Toxicology and Inflammation

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Abstract

Ocular toxicology pertains to toxicological effects on the eye of drugs administered topically, periocularly, intraocularly, or systemically. The ophthalmic examination is able to provide detailed in-life information and is used in combination with clinical observations, clinical pathology, and histopathology to assess potential toxicologic effects. The ophthalmologist must be familiar with the wide range of species used in the field of toxicology, be familiar with the anatomic variations associated with these species, be able to differentiate an inherited or a breed-related finding from a study-related effect, be competent with the required ophthalmic equipment, and be capable of examining this wide range of animals.

Endorsed by the American College of Veterinary Ophthalmologists (ACVO).

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Author information

Authors and Affiliations

  1. Department Chair, Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, USA

    David A. Wilkie, Brian C. Gilger & Joshua T. Bartoe

Authors
  1. David A. Wilkie
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  2. Brian C. Gilger
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  3. Joshua T. Bartoe
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Corresponding author

Correspondence to Brian C. Gilger .

Editor information

Editors and Affiliations

  1. Department of Clinical Sciences, North Carolina State University, Raleigh, NC, USA

    Brian C. Gilger

  2. Veterinary Vision, San Francisco, CA, USA

    Cynthia S. Cook

  3. Veterinary Ophthalmology Services, Inc., Little Falls, NJ, USA

    Michael H. Brown

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Wilkie, D.A., Gilger, B.C., Bartoe, J.T. (2018). Standards for Conducting Ophthalmic Examinations in Laboratory Animals. In: Gilger, B., Cook, C., Brown, M. (eds) Standards for Ocular Toxicology and Inflammation. Springer, Cham. https://doi.org/10.1007/978-3-319-78364-2_1

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