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The Role of Pharmacometrics in the Development of Antimicrobial Agents

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Antimicrobial Resistance in the 21st Century

Part of the book series: Emerging Infectious Diseases of the 21st Century ((EIDC))

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Abstract

We live in a world teeming with antimicrobial-resistant pathogens. For a number of pan-resistant pathogens, our once plentiful antimicrobial armamentarium is now quite limited. There is a critical need for new antimicrobial agents to treat patients with infections due to these highly resistant organisms such as Gram-negative bacilli [1]. The need for new agents is especially great for the treatment of patient populations at great risk for morbidity and mortality, such as those with hospital-acquired and ventilator-associated bacterial pneumonia (HABP and VABP, respectively) arising from resistant pathogens.

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Authors and Affiliations

  1. Institute for Clinical Pharmacodynamics, Schenectady, NY, USA

    Justin C. Bader, Elizabeth A. Lakota, Brian VanScoy, Sujata M. Bhavnani & Paul G. Ambrose

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  1. Justin C. Bader
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  2. Elizabeth A. Lakota
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  3. Brian VanScoy
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  4. Sujata M. Bhavnani
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  5. Paul G. Ambrose
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Correspondence to Sujata M. Bhavnani .

Editor information

Editors and Affiliations

  1. Department of Medicine, University of Toronto, Toronto, ON, Canada

    I. W. Fong

  2. Anti-infectives Consulting, LLC, Stonington, CT, USA

    David Shlaes

  3. Public Health Research Institute, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, NJ, USA

    Karl Drlica

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Bader, J.C., Lakota, E.A., VanScoy, B., Bhavnani, S.M., Ambrose, P.G. (2018). The Role of Pharmacometrics in the Development of Antimicrobial Agents. In: Fong, I., Shlaes, D., Drlica, K. (eds) Antimicrobial Resistance in the 21st Century. Emerging Infectious Diseases of the 21st Century. Springer, Cham. https://doi.org/10.1007/978-3-319-78538-7_22

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