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EUS-Guided Pancreatic Cyst Ablation

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Interventional Endoscopic Ultrasound

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Abstract

The management of pancreatic cystic lesions is often a challenge because surgical intervention can be difficult and associated with serious risks. Often, the patients are elderly and may not tolerate a pancreatic resection, such as a Whipple. Pancreatic cyst ablation therapy may provide an alternative to surgical intervention by providing a minimally invasive approach for cyst eradication. Initial approaches in cyst ablation used ethanol lavage with long-term success rates of about 50%. More recently, taxol injection has been added to ethanol lavage and higher rates of ablation have been seen. Although complication rates are low, new protocols have demonstrated greater safety eliminating ethanol and using a combination of paclitaxel and gemcitabine as ablative agents. Future studies will need to determine long-term outcomes of ablation therapy in randomized controlled trials.

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Author information

Authors and Affiliations

  1. Department of Medicine, Mt. Auburn Hospital, Cambridge, MA, USA

    Kristopher Philogene

  2. Department of Gastroenterology, Mt. Auburn Hospital, Cambridge, MA, USA

    William R. Brugge

Authors
  1. Kristopher Philogene
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  2. William R. Brugge
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Correspondence to William R. Brugge .

Editor information

Editors and Affiliations

  1. Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Utah School of Medicine, Salt Lake City, UT, USA

    Douglas G. Adler, MD, FACG, AGAF, FASGE

Electronic Supplementary Material

Linear EUS video of ethanol injection of a small pancreatic cystadenoma (MP4 11207 kb)

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Philogene, K., Brugge, W.R. (2019). EUS-Guided Pancreatic Cyst Ablation. In: Adler, MD, FACG, AGAF, FASGE, D. (eds) Interventional Endoscopic Ultrasound. Springer, Cham. https://doi.org/10.1007/978-3-319-97376-0_13

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  • DOI: https://doi.org/10.1007/978-3-319-97376-0_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-97375-3

  • Online ISBN: 978-3-319-97376-0

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