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Biologische Funktion der “frühen” Übergangsmetalle: Molybdän, Wolfram, Vanadium, Chrom

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Bioanorganische Chemie

Part of the book series: Teubner Studienbücher Chemie ((TSBC))

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Zusammenfassung

Im Gegensatz zu “späten” Übergangsmetallen wie Cobalt, Nickel oder Kupfer zeichnen sich die Metalle aus dem vorderen Bereich der Übergangsmetallreihen dadurch aus, daß sie unter aeroben Bedingungen in wäßriger Lösung hohe Oxidationsstufen, hohe Koordinationszahlen und “harte”, insbesondere negativ geladene Sauerstoff-Koordinationszentren bevorzugen. In vielen Fällen ergibt sich dadurch eine negative Gesamtladung der resultierenden Oxo- oder Hydroxo-Komplexe, was vor allem im Hinblick auf physiologische Aufnahme- und Mobilisierungs-Mechanismen von Bedeutung ist. Für Scandium und Titan am Beginn der ersten (3d-)Übergangsmetallreihe konnte zwar noch keine physiologische Bedeutung nachgewiesen werden; Vanadium und Chrom sowie dessen schwerere Homologe im Periodensystem, Molybdän und Wolfram, besitzen jedoch recht differenzierte physiologische Funktionen. Das biologisch bedeutendste Element in dieser Reihe ist zweifellos das Molybdän, dessen Chemie und enzymatische Funktionen (Stiefel, Coucouvanis, Newton; Bray; Burgmayer, Stirfrl) im Bereich von Sauerstoff-Übertragung und Stickstoff-Fixierung ausführlicher vorgestellt werden.

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  1. Stuttgart, Deutschland

    Prof. Dr. phil. nat. Wolfgang Kaim & Brigitte Schwederski Ph. D.

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  1. Prof. Dr. phil. nat. Wolfgang Kaim
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© 2004 B. G. Teubner Verlag / GWV Fachverlage GmbH, Wiesbaden

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Kaim, W., Schwederski, B. (2004). Biologische Funktion der “frühen” Übergangsmetalle: Molybdän, Wolfram, Vanadium, Chrom. In: Bioanorganische Chemie. Teubner Studienbücher Chemie. Vieweg+Teubner Verlag. https://doi.org/10.1007/978-3-322-92714-9_11

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  • DOI: https://doi.org/10.1007/978-3-322-92714-9_11

  • Publisher Name: Vieweg+Teubner Verlag

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  • Online ISBN: 978-3-322-92714-9

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