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Post-Activation State: A Critical Rite of Passage of Memories

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Memories: Molecules and Circuits

Part of the book series: Research and Perspectives in Neurosciences ((NEUROSCIENCE))

Abstract

Each memory item has a unique biography. The global outline of the narrative of this biography, however, is shared by different items. The textbook account charts the ontogeny of memory items as a universal linear process. First the new information is encoded. Then it enters a short-term persistence phase, during which it is prone to interference by various types of treatments, ranging from distracting sensory stimuli to physical agents and drugs, collectively termed “amnesic agents”. The period during which the item becomes gradually immune to the effect of amnesic agents is termed “memory consolidation”. Upon completion of consolidation, so goes the zeitgeist, the stabilized item enters into a long-term “store”, from which it can be later retrieved for use.

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Author information

Authors and Affiliations

  1. Department of Neurobiology, The Weizmann Institute of Science, Rehovot, 76100, Israel

    Yadin Dudai

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  1. Yadin Dudai
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Editors and Affiliations

  1. Laboratoire de Neurosciences Cognitives CNRS UMR 5106, Université de Bordeaux 1, Avenue des Facultés, 33405, Talence, France

    Bruno Bontempi Ph.D.

  2. Departments of Neurobiology Psychiatry and Biobehavioral Sciences Psychology and Brain Research Institute, UCLA, 695 Young Drive South Room 2357, Box 951761, Los Angeles, CA, 90095-1761, USA

    Alcino J. Silva (Prof. Dr.) (Prof. Dr.)

  3. Pour la Recherche Thérapeutique, Fondation IPSEN, 24, rue Erlanger, 75781, Paris Cedex 16, France

    Yves Christen Ph.D.

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Dudai, Y. (2007). Post-Activation State: A Critical Rite of Passage of Memories. In: Bontempi, B., Silva, A.J., Christen, Y. (eds) Memories: Molecules and Circuits. Research and Perspectives in Neurosciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-45702-2_5

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