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Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

In most patients suffering from cancer, the primary tumor can be resected in a curative intention. However, during patient’s history, liver metastases occur — depending on the tumor — in up to 70%. There are data from large autopsy studies showing that liver metastases are detectable in more than 40% of all malignancies (Tranberg 2004). Liver metastases therefore have the highest impact on patient’s long-term survival and are responsible for the largest part of cancer-related deaths worldwide (Tranberg 2004). In the western world metastases of colorectal cancer are the most common indication for resection, followed by metastases of breast cancer. It has been shown that the 3-, 5-, and 10-year survival rates after a successful resection of liver metastases are as high as 45%, 30%, and 20% respectively (Ohlsson et al. 1998; Scheele et al. 1995). For this reason, in recent years surgical resection was considered to be the only curative option in liver metastases, while chemotherapy and radiation therapy were viewed as only palliative treatment options.

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References

  • Anderson GS, Brinkmann F, Soulen MC et al (2003) FDG positron emission tomography in the surveillance of hepatic tumors treated with radiofrequency ablation. Clin Nucl Med 28:192–197

    Article  PubMed  Google Scholar 

  • de Baere T, Elias D, Dromain C et al (2000) Radiofrequency ablation of 100 hepatic metastases with a mean follow-up of more than 1 year. AJR Am J Roentgenol 175:1619–1625

    PubMed  Google Scholar 

  • Bilchik AJ, Wood TF, Allegra DP (2001) Radiofrequency ablation of unresectable hepatic malignancies: lessons learned. Oncologist 6:24–33

    Article  PubMed  CAS  Google Scholar 

  • Cioni D, Lencioni R, Bartolozzi C (2001) Percutaneous ablation of liver malignancies: imaging evaluation of treatment response. Eur J Ultrasound 13:73–93

    Article  PubMed  CAS  Google Scholar 

  • Curley SA (2003) Radiofrequency ablation of malignant liver tumors. Ann Surg Oncol 10:338–347

    Article  PubMed  Google Scholar 

  • Curley SA, Izzo F, Delrio P et al (1999) Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients. Ann Surg 230:1–8

    Article  PubMed  CAS  Google Scholar 

  • Curley SA, Izzo F, Ellis LM et al (2000) Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis. Ann Surg 232:381–391

    Article  PubMed  CAS  Google Scholar 

  • Curley SA, Marra P, Beaty K et al (2004) Early and late complications after radiofrequency ablation of malignant liver tumors in 608 patients. Ann Surg 239:450–458

    Article  PubMed  Google Scholar 

  • Donckier V, Van Laethem JL, Goldman S et al (2003) [F-18] fluorodeoxyglucose positron emission tomography as a tool for early recognition of incomplete tumor destruction after radiofrequency ablation for liver metastases. J Surg Oncol 84:215–223

    Article  PubMed  Google Scholar 

  • Erce C, Parks RW (2003) Interstitial ablative techniques for hepatic tumours. Br J Surg 90:272–289

    Article  PubMed  CAS  Google Scholar 

  • Gazelle GS, Goldberg SN, Solbiati L et al (2000) Tumor ablation with radio-frequency energy. Radiology 217:633–646

    PubMed  CAS  Google Scholar 

  • Gillams AR, Lees WR (2004) Radio-frequency ablation of colorectal liver metastases in 167 patients. Eur Radiol 14:2261–2267

    Article  PubMed  CAS  Google Scholar 

  • Goldberg SN, Ahmed M (2002) Minimally invasive image-guided therapies for hepatocellular carcinoma. J Clin Gastroenterol 35:S115–S129

    Article  PubMed  CAS  Google Scholar 

  • Joosten J, Jager G, Oyen W, Wobbes T, Ruers T (2005) Cryosurgery and radiofrequency ablation for unresectable colorectal liver metastases. Eur J Surg Oncol 31:1152–1159

    Article  PubMed  CAS  Google Scholar 

  • Lencioni R, Cioni D, Bartolozzi C (2001) Percutaneous radiofrequency thermal ablation of liver malignancies: techniques, indications, imaging findings, and clinical results. Abdom Imaging 26:345–360

    Article  PubMed  CAS  Google Scholar 

  • Lencioni R, Cioni D, Crocetti L et al (2002) Ultrasound imaging of focal liver lesions with a second-generation contrast agent. Acad Radiol 9[Suppl 2]:S371–374

    Article  PubMed  Google Scholar 

  • Liu LX, Jiang HC, Piao DX (2002) Radiofrequency ablation of liver cancers. World J Gastroenterol 8:393–399

    PubMed  Google Scholar 

  • Livraghi T, Meloni F (2001) Removal of liver tumours using radiofrequency waves. Ann Chir Gynaecol 90:239–245

    PubMed  CAS  Google Scholar 

  • Livraghi T, Solbiati L, Meloni MF et al (2003) Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology 226:441–451

    Article  PubMed  Google Scholar 

  • McGahan JP, Browning PD, Brock JM et al (1990) Hepatic ablation using radiofrequency electrocautery. Invest Radiol 25:267–270

    Article  PubMed  CAS  Google Scholar 

  • Mulier S, Mulier P, Ni Y et al (2002) Complications of radiofrequency coagulation of liver tumours. Br J Surg 89:1206–1222

    Article  PubMed  CAS  Google Scholar 

  • Ohlsson B, Stenram U, Tranberg KG (1998) Resection of colorectal liver metastases: 25-year experience. World J Surg 22:268–276; discussion 276–267

    Article  PubMed  CAS  Google Scholar 

  • Pereira PL, Trubenbach J, Schmidt D (2003) Radiofrequency ablation: basic principles, techniques and challenges. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 175:20–27

    Article  PubMed  CAS  Google Scholar 

  • Rossi S, Fornari F, Pathies C et al (1990) Thermal lesions induced by 480 kHz localized current field in guinea pig and pig liver. Tumori 76:54–57

    PubMed  CAS  Google Scholar 

  • Scheele J, Stang R, Altendorf-Hofmann A et al (1995) Resection of colorectal liver metastases. World J Surg 19:59–71

    Article  PubMed  CAS  Google Scholar 

  • Siperstein AE, Berber E (2001) Cryoablation, percutaneous alcohol injection, and radiofrequency ablation for treatment of neuroendocrine liver metastases. World J Surg 25:693–696

    Article  PubMed  CAS  Google Scholar 

  • Solbiati L, Ierace T, Tonolini M et al (2001) Radiofrequency thermal ablation of hepatic metastases. Eur J Ultrasound 13:149–158

    Article  PubMed  CAS  Google Scholar 

  • Tranberg KG (2004) Percutaneous ablation of liver tumours. Best Pract Res Clin Gastroenterol 18:125–145

    Article  PubMed  Google Scholar 

  • Wood TF, Rose DM, Chung M et al (2000) Radiofrequency ablation of 231 unresectable hepatic tumors: indications, limitations, and complications. Ann Surg Oncol 7:593–600

    PubMed  CAS  Google Scholar 

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© 2008 Springer-Verlag Berlin Heidelberg

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Hoffmann, RT., Jakobs, T.F., Helmberger, T.K., Reiser, M.F. (2008). Radiofrequency Ablation (RFA). In: Vogl, T.J., Helmberger, T.K., Mack, M.G., Reiser, M.F. (eds) Percutaneous Tumor Ablation in Medical Radiology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68250-9_16

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  • DOI: https://doi.org/10.1007/978-3-540-68250-9_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22518-8

  • Online ISBN: 978-3-540-68250-9

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