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Neonatale Cholestase

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Pädiatrische Gastroenterologie, Hepatologie und Ernährung

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Als idiopathische neonatale Hepatitis (INH) bezeichnet man eine neonatale cholestatische Erkrankung, bei der die Vielzahl anderer ätiologischer Ursachen (⊡ Tab. 16.1) ausgeschlossen werden konnten. Histopathologisch ist sie durch sog. Riesenzellen gekennzeichnet und wurde deshalb auch als »Riesenzellhepatitis« bezeichnet. Zunächst wurde die INH in 30–40% aller Fälle mit neonataler Cholestase diagnostiziert, wegen verbesserter diagnostischer Möglichkeiten nimmt ihr Anteil in jüngeren Studien jedoch deutlich ab - was darauf hindeutet, dass die INH keine eigenständige Entität, sondern einen Sammeltopf verschiedener Formen der neonatalen Cholestase darstellt.

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Authors and Affiliations

  1. Klinikum der Universität Regensburg, Kinder UNi Klinik Ostbayern (KUNO), Franz-Josef-Strauss-Allee 11, 93053, Regensburg

    M. Melter Prof. Dr.

  2. Kinderchirurgische Klinik der MHH, Carl-Neuberg-Str. 1, 30625, Hannover

    C. Petersen Prof. Dr.

  3. Universitätskinderklinik, Hoppe-Seyler-Str. 1, 72070, Tübingen

    E. Sturm Prof. Dr.

Authors
  1. M. Melter Prof. Dr.
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  2. C. Petersen Prof. Dr.
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  3. E. Sturm Prof. Dr.
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Editors and Affiliations

  1. Klinik für Kinder- und Jugendmedizin, Marienhospital Osnabrück, Johannisfreiheit 2-4, 49074, Osnabrück

    Burkhard Rodeck

  2. Universitätsklinikum Gießen und Marburg GmbH Zentrum für Kinderheilkunde und Jugendmedizin Abt. Allgemeine Pädiatrie und Neonatologie, Justus-Liebig-Universität, Feulgenstr. 12, 35385, Gießn

    Klaus-Peter Zimmer

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Melter, M., Petersen, C., Sturm, E. (2008). Neonatale Cholestase. In: Rodeck, B., Zimmer, KP. (eds) Pädiatrische Gastroenterologie, Hepatologie und Ernährung. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73969-2_16

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  • DOI: https://doi.org/10.1007/978-3-540-73969-2_16

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