Skip to main content
SpringerLink
Log in

Hepatomegaly and splenomegaly

  • Chapter
Hepatology Textbook and Atlas

  • 3352 Accesses

Abstract

Hepatomegaly is present if (1.) palpation locates the lower border of the right lobe of liver to be more than 2 cm (one to two finger breadths) below the left costal arch (MCL lateral to rectus abdominis) (caution: phrenoptosis), (2.) the absolute liver dullness on percussion is more than 14 cm, or (3.) the longitudinal diameter of the liver in the MCL is greater than approximately 15 cm in the sonogram.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Dockter, G., Sitzmann, F.C.: Hepatosplenomegalie im Kindesalter — vom Symptom zur Diagnose. Med. Welt 1988; 39: 1287–1292

    Google Scholar 

  2. Garcia Reinoso, C., Saez-Royuela, F., Gomez Rubio, M., Gomez Carrascal, C., Miranda Baiocchi, R., Hernandez Guio, C.: Formas de presentation y procedimientos diagnosticos del hemangioma hepatico gigante. Rev. Esp. Enf. Ap. Digest. 1989; 76: 617–621

    CAS  Google Scholar 

  3. Götz, G.F., Mathias, K., Dykgers, A.: Neuroblastom IV-S. Kasuistischer Beitrag zur Hepatomegalie. Fortschr. Röntgenstr. 1987; 147: 91–93

    Article  Google Scholar 

  4. Gosink, B., Leymaster, C.: Ultrasonic determination of hepatomegaly. J. Clin. Ultrasound 1981; 9: 37–41

    Article  PubMed  CAS  Google Scholar 

  5. Müllhaupt, B., Steuser, J., Vetter, W.: Fettunverträglichkeit, Druck im rechten Oberbauch, Hepatomegalie. Schweiz. Rundsch. Med. (Praxis) 1990: 79: 639–642

    Google Scholar 

  6. Ortega Calvo, M., Corchado Albalat, Y., Fuentes Verdera, M., Griera Borras, J.L., Martinez Manzanares, C.: Aspectos clinicos de la hepatomegalia de estasis. Rev. Esp. Enf. Ap. Digest. 1989; 76: 612–616

    CAS  Google Scholar 

  7. Schneider, J.G., Schaefer, S., Lettgen, B., Keiper, T., Nawroth, P.P., Dugl, K.A.: Siblings with hepatosplenomegaly and lipoprotein lipase deficiency. Lancet 2002; 360: 1150.

    Article  PubMed  Google Scholar 

  8. Serra, L., Poppi, M.C., Criscuolo, M., Zandomeneghi, R.: Primary systemic amyloidosis with giant hepatomegaly and portal hypertension: a case report and a review of the literature. Ital. J. Gastroenterol. 1993; 25: 435–438

    CAS  Google Scholar 

  9. Thiel, van, D.H., Hagler, N.G., Schade, R.R., Skolnick, M.L., Pollitt Heyl, A., Rosenblum, E., Gavaler, J.S., Penkrot, R.J.: In vivo hepatic volume determination using sonography and computed tomography. Gastroenterology 1985; 88: 1812–1817

    PubMed  Google Scholar 

  10. Urganci, N., Arapoglu, M., Evrüke, M., Aydin, A.: A rare cause of hepatomegaly: 3-hydroxy-3-methylglutaryl coenzyme-A lyase deficiency. J. Pediatr. Gastroenterol Nutr. 2001; 33: 339–341

    Article  PubMed  CAS  Google Scholar 

  11. Wolf, A., Lavine, J.: Hepatomegaly in neonates and children Pediatr. Rev. 2000; 21: 303–310

    CAS  Google Scholar 

Splenomegaly

  1. Akoh, J.A., Auld, C.D.: Splenic abscess: is conservation applicable? Brit. J. Clin. Pract. 1992; 46: 274–275

    PubMed  CAS  Google Scholar 

  2. Al Mohaya, S., Al-Awami, M., Vaidya, M.P., Knox-Macaulay, H.: Hydatid cyst of the spleen. Amer. J. Trop. Med. Hyg. 1986; 35: 995–999

    Google Scholar 

  3. Berquist, W.E., Diament, M., Fonkalsrud, E.W.: Splenic cyst presenting as a gastric mass. J. Pediatr. Gastroenterol. Nutrit. 1984; 3: 805–807

    Article  CAS  Google Scholar 

  4. Burrig, K.F.: Epithelial (true) splenic cysts. Pathogenesis of the mesothelial and so-called epidermoid cyst of the spleen. Amer. J. Surg. Pathol. 1988; 12: 275–281

    CAS  Google Scholar 

  5. Caslowitz, P.L., Labs, J.D., Fishman, E.K., Siegelman, S.S.: Nontraumatic focal lesions of the spleen: assessment of imaging and clinical evaluation. Comput. Med. Imaging Graph. 1990; 14: 133–141

    Article  PubMed  CAS  Google Scholar 

  6. Dachman, A.H., Ros, P.R., Murari, P.J., Olmsted, W.W., Lichtenstein, J.F.: Nonparasitic splenic cysts: a report of 52 cases with radiologicpathologic correlation. Amer. J. Roentgenol. 1986; 147: 537–542

    CAS  Google Scholar 

  7. Doll, M., Schölmerich, J., Spamer, C., Volk, B.A., Gerok, W.: Klinische Bedeutung der sonographisch festgestellten Splenomegalie. Dtsch. Med. Wschr. 1986; 111: 887–891

    PubMed  CAS  Google Scholar 

  8. Ebaugh, F.G. jr., McIntyre, O.R.: Palpable spleens: ten years follow-up. Ann. Intern. Med. 1979; 90: 130–131

    PubMed  Google Scholar 

  9. Gusberg, R.J., Peterec, S.M., Sumpio, B.E., Meier, G.H.: Splenomegaly and variceal bleeding — hemodynamic basis and treatment implications. Hepato-Gastroenterol. 1994; 41: 573–577

    CAS  Google Scholar 

  10. Guzzetta, P.C., Ruley, E.J., Merrick, H.F., Verderese, C., Barton, N.: Elective subtotal splenectomy. Indications and results in 33 patients. Ann. Surg. 1990; 211: 34–42

    Article  PubMed  CAS  Google Scholar 

  11. Horber, F.F., Lerut, J.P., Reichen, J., Zimmermann, A., Jaeger P., Malinverni, R.: Visceral leishmaniasis after orthotopic liver transplantation: impact of persistent splenomegaly. Transpl. Int. 1993; 6: 55–57

    Article  PubMed  CAS  Google Scholar 

  12. Johnson, H.A., Deterling, R.A.: Massive splenomegaly. Surg. Gynec. Obstetr. 1989; 168: 131–137

    CAS  Google Scholar 

  13. Klee, F.E., Osswald, B.R., Wysocki, S.: Cyst of the spleen — classical incidental diagnosis? Zb. Chir. 1996; 121: 805–816

    CAS  Google Scholar 

  14. Knaut, S., Ludtke-Handjery, A., Anbuth, D.: Die posttraumatische Milzzyste. Zentralbl. Chir. 1988; 113: 42–47

    PubMed  CAS  Google Scholar 

  15. Korn, M.A., Mostbeck, G.H., Tscholakoff, D.: Duplexsonographie: Echoreiche Milzzyste oder Splenomegalie? Röntgenblätter 1990; 43: 107–108

    PubMed  CAS  Google Scholar 

  16. Manesis, E., Zoumboulis, P., Georgiou, S., Vardaka, J., Hadziqannis, St.: Splenomegaly in asymptomatic chronic carriers of hepatitis B and D viruses. Eur. J. Gastroenterol. Hepatol. 1994; 6: 793–796

    Article  Google Scholar 

  17. Manoharan, A., Bader, L.V., Pitney, W.R.: Non-tropical idiopathic splenomegaly (Dacie’s syndrome). Report of 5 cases. Scand. J. Haematol. 1982; 28: 175–179

    PubMed  CAS  Google Scholar 

  18. Meran, J., Creutzig, A., Specht, S., Schürmeyer, Th., Brunner, G., Ranke, C., Fabel, H.: Portale, Hypertension und chronische Arsenexposition. Wien. Med. Wschr. 1989; 139: 580–584

    PubMed  CAS  Google Scholar 

  19. Ohta, M., Tsutsumi, Y., Tanaka, Y.: Splenic hamartoma. Acta Pathol. Jpn. 1986; 36: 471–480

    PubMed  CAS  Google Scholar 

  20. Piontek, M., Hengels, K.J., Borchard, F., Strohmeyer, G.: Nicht-zirrhotische Leberfibrose nach chronischer Arsenintoxikation. Dtsch. Med. Wschr. 1989; 114: 1653–1657

    PubMed  CAS  Google Scholar 

  21. Ramer, M., Diznoff, S.B., Hewes, A.C.: Intrasplenic pancreatic pseudocyst: another cause of splenomegaly. Clin. Radiol. 1974; 25: 525–529

    Article  PubMed  CAS  Google Scholar 

  22. Reynolds, M., Donaldson, J.S., Vogelzar, R.L.: Giant jatrogenic splenic pseudocyst. J. Pediatr., Surg. 1989; 24: 700–701

    Article  CAS  Google Scholar 

  23. Schloesser, L.L.: The diagnostic significance of splenomegaly. Amer. J. Med. Sci. 1963; 245: 118–124

    Article  Google Scholar 

  24. Schölmerich, J.: Diagnostische Maßnahmen bei Splenomegalie. Dtsch. Med. Wschr. 1986; 111: 903–905

    PubMed  Google Scholar 

  25. Sekiya, T., Meller, S.T., Cosgrove, D.O., McCready, V.R.: Ultrasonography of Hodgkin’s disease in the liver and spleen. Clin. Radiol. 1982; 33: 635–639

    Article  PubMed  CAS  Google Scholar 

  26. Sheth, S.G., Amarapurkar, D.N., Chopra, K.B., Mani, S.A., Mehta, P.J.: Evaluation of splenomegaly in portal hypertension. J. Clin. Gastroenterol. 1996; 22: 28–30

    Article  PubMed  CAS  Google Scholar 

  27. Waller, H.D.: Differentialdiagnose des Milztumors. Therapiewoche 1975; 35: 4720–4732

    Google Scholar 

  28. Warfel, K.A., Ellis, G.H.: Peliosis of the spleen. Reports of a case and review of the literature. Arch. Pathol. Med. 1982; 106: 99–100

    CAS  Google Scholar 

  29. Welten, C.A., Sijbrandij, E.S.: Familial nonparasitic, splenic cysts. Netherl. J. Med 1992; 40: 236–239

    CAS  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

(2008). Hepatomegaly and splenomegaly. In: Hepatology Textbook and Atlas. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76839-5_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-76839-5_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-76838-8

  • Online ISBN: 978-3-540-76839-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation