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Evaluation of Spontaneous and Therapeutically Induced Apoptosis in Childhood Leukemias

  • Conference paper
Acute Leukemias VIII

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 40))

  • 106 Accesses

Abstract

AIM: To observe the sequence of spontaneous apoptosis and apoptosis after treatment in acute lymphoblastic leukemia (ALL) in children.

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References

  1. Thatte U, Dahanukar S (1997) Apoptosis. Clinical relevance and pharmacological manipulation. Drugs 54:511–532

    Article  PubMed  CAS  Google Scholar 

  2. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C (1995) A novel assay for apoptosis flow cytometric detection of phosphatidyserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Meth 184:39–51

    Article  CAS  Google Scholar 

  3. Koopman G, Reutelingsperger GAM, Kuijten RMJ, Keehnen ST, Pals ST, van Oers MHJ (1994) Annexin V for flow cytometric Detection of Phosphatidylserine Expression on B cells undergoing Aapoptosis. Blood 84:1415–1420

    PubMed  CAS  Google Scholar 

  4. Martin SJ, Reutelingsperger CPM, McGahon AJ, Rader JA, van Schie RCAA, LaFace DM, Green DR (1995) Early Redistribution of plasma membrane Phosphatidylserine is a general Feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of bcl-2 and abl. J Exp Med. 182:1545–1556

    Article  PubMed  CAS  Google Scholar 

  5. Nicoletti I, Migliorati G, Pagliacci M., Grignani F, Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Meth 139:271–279

    Article  CAS  Google Scholar 

  6. Li J, Eastman A (1995) Apoptosis in an Interleukin-2-dependent Cytotoxic T lymphocyte cell line is associated with intracellular acidification. J Biol Chem 270:3202–3211

    Google Scholar 

  7. Barry MA, Reynolds JE, Eastman A (1993) Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification. Cancer Res 53:2349–2357

    PubMed  CAS  Google Scholar 

  8. Karwatowska-Prokopczuk E, Nordberg JA, Li HL, Engler RL, Gottlieb RA (1998) Effect of vacuolar proton ATPase on pHi, Ca 2+ and apoptosis in neonatal cardiomyocytes during metabolic inhibition/recovery. Circ Res 82:1139–1144

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Paediatrics, Haematology and Oncology; Department of Laboratory Diagnostics and Immunology, Medical University of Warsaw, Poland, USA

    I. Malinowska, M. Wasik, A. Stelmaszczyk, E. Górska, M. Steczowicz & R. Rokicka-Milewska

Authors
  1. I. Malinowska
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  2. M. Wasik
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  3. A. Stelmaszczyk
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  4. E. Górska
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  5. M. Steczowicz
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  6. R. Rokicka-Milewska
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine A, Germany

    T. Büchner

  2. Department of Internal Medicine III, University Hospital Großhadern Ludwig-Maximilians-University, Marchioninistr. 15, 81377, München, Germany

    W. Hiddemann

  3. Dept. of Internal Medicine, University of Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany

    B. Wörmann

  4. Department of Pediatrics, University of Münster, Albert-Schweitzer-Straße 33, 48149, Münster, Germany

    G. Schellong , J. Ritter  & U. Creutzig ,  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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Malinowska, I., Wasik, M., Stelmaszczyk, A., Górska, E., Steczowicz, M., Rokicka-Milewska, R. (2001). Evaluation of Spontaneous and Therapeutically Induced Apoptosis in Childhood Leukemias. In: Büchner, T., Hiddemann, W., Wörmann, B., Schellong, G., Ritter, J., Creutzig, U. (eds) Acute Leukemias VIII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 40. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18156-6_22

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  • DOI: https://doi.org/10.1007/978-3-642-18156-6_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62109-3

  • Online ISBN: 978-3-642-18156-6

  • eBook Packages: Springer Book Archive

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