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Packaging in Synthetic Biology

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Bio and Nano Packaging Techniques for Electron Devices

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Abstract

In modern biosciences, the biological cell is perceived as a mechanistic system similar to a factory or a highly integrated technical device consisting of a set of different interacting machines which are built from parts acting by mechanical and even electronic means. In this concept, the biological cell represents an extraordinary example for a high level of packaging which is without comparison in technical disciplines created by mankind. Concerning packaging the cell membrane plays a crucial role since it does not only define the spatial boundary of the cell but also provides the platform for many functional elements and regulates the communication of the cell with the environment and neighboring cells. Furthermore, biological matter as a machinery shows characteristics that makes it preferable over technical machinery, namely the capability of adaption, self-repair, self-assembly and even self-replication. If one is interested not only in investigating this issue but is interested in an engineering approach to build functional systems following the biological concept of packaging, the bottom-up synthetic biology is the choice of method. This chapter presents approaches in synthetic biology using biomembranes and membrane proteins for biological packaging.

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  1. Biotechnology Center, Technische Universität Dresden, 01062, Dresden, Germany

    Jakob Schweizer, Matthias Garten & Petra Schwille

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  2. Matthias Garten
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  1. Fak. Elektrotechnik, Inst. Festkörperelektronik, TU Dresden, Helmholtzstr. 18, Dresden, 01069, Sachsen, Germany

    Gerald Gerlach

  2. Fak. Elektrotechnik und, Informationstechnik, TU Dresden, Mommsenstr. 13, Dresden, 01069, Sachsen, Germany

    Klaus-Jürgen Wolter

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Schweizer, J., Garten, M., Schwille, P. (2012). Packaging in Synthetic Biology. In: Gerlach, G., Wolter, KJ. (eds) Bio and Nano Packaging Techniques for Electron Devices. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28522-6_19

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