Abstract
The activity of serum enzymes depends on their rates of entrance as well of elimination (or inactivation). Since previous observations were contradictory, we investigated G.O.T. in the blood of rats following ligature of the left liver lobe and after recirculation; an increase in S.G.O.T. occurred. Following i.v. injection of G.O.T., its excretion via the bile is considerably enhanced; however, only a small fraction of injected G.O.T. can be recovered. Addition of lung slices in vitro greatly increases G.O.T. inactivation. Some implications for the interpretation of S.G.O.T. increase are discussed.
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References
Chinsky, M., and S. Sherry: Arch. Int. Med. 99, 556 (1957).
Clermont, R. J., and T. C. Chalmers: Medicine 46, 197 (1967).
Dunn, N., et al.: J. Lab. Clin. Med. 51, 259 (1958).
Lorentz, K.: Acta Hepato-Splen. 9, 403 (1962).
Zolton, T., et al.: Arch. Environ. Health 2, 16 (1960).
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© 1968 Springer-Verlag Berlin · Heidelberg
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Fischer, A., Takacs, L. (1968). On the Release and Elimination of Liver Glutamic-Oxalacetic-Transferase. In: Locker, A. (eds) Quantitative Biology of Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51065-6_26
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DOI: https://doi.org/10.1007/978-3-642-51065-6_26
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-04301-0
Online ISBN: 978-3-642-51065-6
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