Abstract
Hypotension due to peripheral vasodilation and reduced responsiveness to vasopressor therapy are cardinal features of septic, and other forms of vasodilatory, shock. The nonosmotic release of the peptide hormone arginine-vasopressin in response to hypotension and hypovolemia, is an important defense mechanism to counteract systemic hypotension and maintain adequate tissue perfusion. Despite an initial appropriate response, vasopressin plasma levels fall and are inappropriately low in later stages of septic shock [1].
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Auzinger, G., Wendon, J. (2002). Vasopressin and its Analogs. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2002. Yearbook of Intensive Care and Emergency Medicine 2002, vol 2002. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56011-8_21
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DOI: https://doi.org/10.1007/978-3-642-56011-8_21
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