Skip to main content
SpringerLink
Log in

Akute Schädel-Hirn-Verletzung

Pathophysiologie, Monitoring und Therapie

  • Chapter
Weiterbildung für Anästhesisten 2000

Zusammenfassung

Dem Zentralnervensystem kommt eine Schlüsselstellung für die adäquate Funktion von Organen und Organsystemen im menschlichen Körper zu, insbesorders die Regulation von Atmung, Kreislauf sowie humoraler und immunologischer Systeme. Hirnverletzungen beeinträchtigen daher nicht nur das Zentralnervensystem, sondern den gesamten Organismus. Sie müssen in einer umfassenden Art und Weise behandelt werden, um optimale Bedingung für die Vermeidung von Sekundärläsionen am Gehirn und anderen Organen zu schaffen und die Erholung nicht irreversibel geschädigter Abschnitte des Gehirns zu ermöglichen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 74.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Demann D, Leisman G. (1990) Biomechanics of head injury. Int J Neurosci 54: 101–17

    Article  PubMed  CAS  Google Scholar 

  2. Povlishock JT, Christman CW (1995) The pathobiology of traumatically induced axonal injury in animals and humans: a review of current thoughts. J Neurotrauma 12: 555–64

    Article  PubMed  CAS  Google Scholar 

  3. Graham DI, Ford I, Adams JH, Doyle D, Teasdale GM, Lawrence, et al., (1989) Ischaemic brain damage is still common in fatal non-missile head injury. J Neurol Neurosurg Psychiatry 52: 346–50

    Article  PubMed  CAS  Google Scholar 

  4. Chesnut RM, Marshall LF, Klauber MR, Blunt BA, Baldwin N, Eisenberg HM et al., (1993) The role of secondary brain injury in determining outcome from severe head injury. J Trauma 34: 216–22

    Article  PubMed  CAS  Google Scholar 

  5. Maset AL, Marmarou A, Ward JD, Choi S, Lutz HA, Brooks D, Moulton RJ, DeSalles A, Muizelaar JP, Turner H., et al.(1989) Pressure-volume index in head injury. J Neurosurg 67 832–40

    Google Scholar 

  6. Schneider GH, von-Helden A, Lanksch WR, Unterberg A. (1995) Continuous monitoring of jugular bulb oxygen saturation in comatose patients-therapeutic implications. Acta NeurochirWien 134: 71–5

    Article  CAS  Google Scholar 

  7. Fandino J, Stocker R, Prokop S, Imhof HG (2000) Cerebral oxygenation and systemic trauma-related factors determining neurological outcome after brain injury. J Clin Neurosci 7: 226–33

    Article  PubMed  CAS  Google Scholar 

  8. McLaughlin MR, Marion DW (1996) Cerebral blood flow and vasoresponsivity within and around cerebral contusions. J Neurosurg 85: 871–6

    Article  PubMed  CAS  Google Scholar 

  9. Imhof HG, Gutling E, Ruttner B, Dolder E, Zollinger A, Walser H. (1993) Prognostische Bedeutung derfruh abgeleiteten somatosensorischen evozierten Potentiale bei neurologisch nicht beurteilbaren Patienten nach Schadel-Hirn-Traumen. AktTraumatol 23: 7–13

    CAS  Google Scholar 

  10. Imhof HG, Wacker J, Kach K, Platz A, Trentz O. (1993) Computerized tomography follow-up in the acute phase after craniocerebral trauma. Helv Chir Acta 60: 195–200

    PubMed  CAS  Google Scholar 

  11. Stringer WA, Hasso AN, Thompson JR, Hinshaw DB, Jordan KG (1993) Hyperventilation-induced cerebral ischemia in patients with acute brain lesions: demonstration by xenon-enhanced CT. Am J Neuroradiol 14: 475–84

    PubMed  CAS  Google Scholar 

  12. Yundt KD, Diringer MN (1997) The use of hyperventilation and its impact on cerebral ischemia in the treatment of traumatic brain injury. Crit Care Clin 13: 163–84

    Article  PubMed  CAS  Google Scholar 

  13. Muizelaar JP, Marmarou A, Ward JD, Kontos HA, Choi SC, Becker DP, Gruemer H, Young HF (1991) Adverse effects of prolonged hyperventilation in patients with severe head injury: a randomized clinical trial. J Neurosurg 75: 731–739

    Article  PubMed  CAS  Google Scholar 

  14. Dings J, Meixensberger J, Amschler J, Roosen K. (1996) Continuous monitoring of brain tissue PO2: a new tool to minimize the risk of ischemia caused by hyperventilation therapy. Zentralbl Neurochir 57: 177–83

    PubMed  CAS  Google Scholar 

  15. Clifton GL, Allen-S, Barrodale P, Plenger P, Berry J, Koch S, Fletcher J, Hayes RL, Choi SC (1993) A phase II study of moderate hypothermia in severe brain injury. J Neurotrauma 10: 263–71

    Article  PubMed  CAS  Google Scholar 

  16. Marion DW, Obrist WD, Carlier PM, Penrod LE, Darby JM (1993) The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report. J Neurosurg 79: 354–62

    Article  PubMed  CAS  Google Scholar 

  17. Shiozaki T, Sugimoto H, Taneda M, Yoshida H, Iwai A, Yoshioka T, Sugimoto T. (1993) Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury. J Neurosurg 79: 363–8

    Article  PubMed  CAS  Google Scholar 

  18. Rosner MJ, Rosner SD, Johnson AH (1995) Cerebral perfusion pressure: management protocol and clinical results. J Neurosurg 83: 949–62

    Article  PubMed  CAS  Google Scholar 

  19. Dearden NM (1998) Mechanisms and prevention of secondary brain damage during intensive care. Clin Neuropathol 17: 221–8

    PubMed  CAS  Google Scholar 

  20. Guerra WK, Gaab MR, Dietz H, Mueller JU, Piek J, Fritsch MJ (1999) Surgical decompression for traumatic brain swelling: indications and results. J Neurosurg 90: 187–96

    Article  PubMed  CAS  Google Scholar 

  21. Unterberg AW, Kiening KL, Hartl R, Bardt T, Sarrafzadeh AS, Lanksch WR (1997) Multimodal monitoring in patients with head injury: evaluation of the effects of treatment on cerebral oxygenation. J Trauma 42 (5 Suppl): 32–7

    Article  Google Scholar 

  22. Brain Trauma Foundation (1996) The use of mannitol in severe head injury. J Neurotrauma 13:705-9

    Google Scholar 

  23. Bullock R. (1996) Brain Trauma Foundation. The use of mannitol in severe head injury. J Neurotrauma 13: 705–9

    Article  Google Scholar 

  24. Chestnut RM (1995) Mannitol and other diuretics in severe neurotrauma. New Horiz 3: 448–52

    Google Scholar 

  25. Stover JF, Pleines UE, Morganti-Kossmann MC, Stocker R, Kossmann T. (1999) Thiopental attenuates energetic impairment but fails to normalize cerebrospinal fluid glutamate in brain-injured patients. Crit Care Med 27:1351–7

    Article  PubMed  CAS  Google Scholar 

  26. Stover JF, Stocker R. (1998) Barbiturate coma may promote reversible bone marrow suppression in patients with severe isolated traumatic brain injury. Eur J Clin Pharmacol 54: 529–34

    Article  PubMed  CAS  Google Scholar 

  27. Alderson P, Roberts I. (1999) Corticosteroids for acute traumatic brain injury (Cochrane Review). The Cochrane Library, issue 2,Oxford, Update Software

    Google Scholar 

  28. Mayberg MR (1998) Cerebral vasospasm. Neurosurg Clin N Am 9: 615–27

    PubMed  CAS  Google Scholar 

  29. Murray-GD, Teasdale-GM, Schmitz-H. (1996) Nimodipine in traumatic subarachnoidal hemorrhage: a re-analysis of the HIT I and HIT II trials. Acta Neurochir Wien 138: 1163–67

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chirurgische Intensivmedizin, Departement Chirurgie, Universitätsspital, 8091, Zürich, Germany

    PD Dr. R. Stocker & U. Bürgi

  2. Klinik für Neurochirurgie, Universitätsspital, Zürich, Germany

    E. Keller & H. G. Imhof

Authors
  1. PD Dr. R. Stocker
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. U. Bürgi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Keller
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. G. Imhof
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik für Anästhesiologie, Universität Heidelberg, Im Neuenheimer Feld 110, D-69120, Heidelberg, Germany

    Hubert J. Bardenheuer

  2. Klinik für Anästhesiologie und operative Intensivmedizin, Zentralklinikum, Stenglinstraße 2, D-86156, Augsburg, Germany

    Helmuth Forst

  3. Klinik für Anästhesiologie, Medizinische Einrichtungen der RWTH Aachen, Pauwelsstraße 30, D-52074, Aachen, Germany

    Rolf Rossaint

  4. Service d’Anesthésiologie Centre Hospitalier, Universitaire Vaudois — CHUV, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland

    Donat R. Spahn

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Stocker, R., Bürgi, U., Keller, E., Imhof, H.G. (2001). Akute Schädel-Hirn-Verletzung. In: Bardenheuer, H.J., Forst, H., Rossaint, R., Spahn, D.R. (eds) Weiterbildung für Anästhesisten 2000. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56596-0_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-56596-0_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41277-9

  • Online ISBN: 978-3-642-56596-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation