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Role of Inflammatory Response and Thrombosis in Acute Coronary Syndromes

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Coronary Circulation and Myocardial Ischemia

Part of the book series: Update in Intensive Care Medicine ((UICMSOFT,volume 32))

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Abstract

Atherosclerotic involvement of coronary arteries is the underlying process in the majority of ischemic heart diseases. Atherosclerotic lesions may cause stable syndromes of ischemia by means of direct luminal arterial narrowing (stable lesions) or unstable or acute ischemic syndromes by inducing intraluminal thrombus formation (unstable lesions). Clinical consequences of coronary lesions will depend on the degree and acuteness of blood flow obstruction, the duration of decreased perfusion and the relative myocardial oxygen demand at the time of blood flow obstruction.

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  1. Unidad de Hemodinámica y Cardiologia Intervencionista, Hospital Universitario San Carlos, Madrid, Spain

    A. Fernández Ortiz

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  1. A. Fernández Ortiz
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Editors and Affiliations

  1. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

    Michael R. Pinsky MD, CM, FCCP, FCCM (Director of Research Division of Critical Care Medicine Professor of Anesthesiology and Critical Care Medicine) (Director of Research Division of Critical Care Medicine Professor of Anesthesiology and Critical Care Medicine)

  2. Department of Cell Biology and Physiology, Autonomous University, Barcelona, Spain

    Antonio Artigas MD, PhD (Director of Critical Care Center Sabadell Hospital Associate Professor) (Director of Critical Care Center Sabadell Hospital Associate Professor)

  3. Paris, France

    Jean-Francois Dhainaut MD, PhD (Director of Medical Intensive Care Unit Dean of Cochin Port-Royal Medical School Vice-President of Paris University) (Director of Medical Intensive Care Unit Dean of Cochin Port-Royal Medical School Vice-President of Paris University)

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Fernández Ortiz, A. (2002). Role of Inflammatory Response and Thrombosis in Acute Coronary Syndromes. In: Pinsky, M.R., Artigas, A., Dhainaut, JF. (eds) Coronary Circulation and Myocardial Ischemia. Update in Intensive Care Medicine, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57212-8_5

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