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Developing Thymocytes Organize Thymic Microenvironments

  • Conference paper
Lymphoid Organogenesis

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 251))

Abstract

The complex mechanisms underlying the development and functioning of the immune system depend on microenvironments in primary and secondary lymphoid organs as regulatory elements. Within a system of millions of different migratory cell types, microenvironments allow cells to meet and to interact with each other. Cellular interaction between specialized cell types and local variations in the concentration and type of soluble mediators control the divergence of immunological reactions within microenvironments.

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Author information

Authors and Affiliations

  1. Department of Immunology, Erasmus University Rotterdam, Rotterdam, The Netherlands

    W. van Ewijk

  2. Department of Immunology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

    H. Kawamoto & Y. Katsura

  3. Department of Immunology, University Hospital Utrecht, Utrecht, The Netherlands

    W. T. V. Germeraad

Authors
  1. W. van Ewijk
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  2. H. Kawamoto
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  3. W. T. V. Germeraad
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  4. Y. Katsura
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Editor information

Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstr. 487, CH-4005, Basel, Switzerland

    Fritz Melchers Ph.D.

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© 2000 Springer-Verlag Berlin Heidelberg

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van Ewijk, W., Kawamoto, H., Germeraad, W.T.V., Katsura, Y. (2000). Developing Thymocytes Organize Thymic Microenvironments. In: Melchers, F. (eds) Lymphoid Organogenesis. Current Topics in Microbiology and Immunology, vol 251. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57276-0_16

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  • DOI: https://doi.org/10.1007/978-3-642-57276-0_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63186-3

  • Online ISBN: 978-3-642-57276-0

  • eBook Packages: Springer Book Archive

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