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Chronische myeloische Leukämie und andere chronische myeloproliferative Erkrankungen

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Molekularmedizinische Grundlagen von hämatologischen Neoplasien

Part of the book series: Molekulare Medizin ((MOLMED))

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Zusammenfassung

Unter dem Oberbegriff der chronischen myeloproliferativen Erkrankungen (CMPE) fassen wir

  • die chronische myeloische Leukämie (CML),

  • die Polycythaemia vera (PV),

  • die idiopathische Osteomyelofibrose (OMS) und

  • die essenzielle Thrombozythämie (ET)

zusammen. Die CMPE treten sporadisch auf, gehen somit auf erworbene und nicht auf angeborene klonale genetische Veränderungen zurück. In allen Fällen sind als Ausgangszellen pluripotente hämatopoetische Stammzellen anzunehmen.

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Haferlach, T., Schnittger, S., Schoch, C. (2003). Chronische myeloische Leukämie und andere chronische myeloproliferative Erkrankungen. In: Ganten, D., Ruckpaul, K., Schlegelberger, B., Fonatsch, C. (eds) Molekularmedizinische Grundlagen von hämatologischen Neoplasien. Molekulare Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59343-7_8

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  • DOI: https://doi.org/10.1007/978-3-642-59343-7_8

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