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External Beam Radiotherapy for Localized Prostatic Cancer at Stanford: Update at the 38th Year

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Carcinoma of the Prostate

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

It has been 85 years since Pasteau (1911) in France, and Paschkis and Tittinger (1910) in Austria introduced gamma irradiation through intraurethral radium sources for the treatment of prostatic cancer. Since then, a wide variety of radiation sources have been used in the treatment of this neoplasm (Table 17.1) (Bagshaw 1993). Currently, external beam x-irradiation derived from mid- to high-energy linear accelerators (6–25 MV) is the most widely employed modality, although ultrasound-guided interstitial irradiation is also used. External beam irradiation at 4, 6, and 15 MV has been utilized at Stanford since 1956 in the treatment of 1318 patients with prostatic cancer treated through December 1994. These cases provide the major database for this report.

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References

  • Bagshaw MA (1992) Carcinoma of the prostate. In: Levitt SH, Khan FM, Potish RS (eds), Levitt and Tapley’s technological basis of radiation therapy: practical clinical applications. Lea & Febiger, Philadelphia, pp 300–322

    Google Scholar 

  • Bagshaw MA (1993) The challenge of radiation treatment of carcinoma of the prostate. In: Lepor H, Lawson RK (eds) Prostate diseases. Saunders, Philadelphia, pp 326–346

    Google Scholar 

  • Bagshaw MA, Kaplan HS (1962) Radical external radiation therapy of localized prostatic carcinom. Proceedings of Tenth International Congress of Radiology, September 1962

    Google Scholar 

  • Bagshaw MA, Kaplan HS, Sagerman RH (1965) Linear accelerator supervoltage radiotherapy. VII. Carcinoma of the prostate. Radiology 85: 121–129

    PubMed  CAS  Google Scholar 

  • Bagshaw MA, Cox RS, Hancock SL (1994) Control of prostate cancer with radiotherapy: long-term results. J Urol 152: 1781–1785

    PubMed  CAS  Google Scholar 

  • Barringer BS (1922) Carcinoma of prostate. Surg Gynecol Obstet 34: 168

    Google Scholar 

  • Beahrs OH, Henson DE, Hutter RVP, Kennedy BJ (1992) Manual for staging of cancer. American Joint Committee on Cancer, 4th edn. Lippincott, Philadelphia

    Google Scholar 

  • Budhraja SN, Anderson JC (1964) An assessment of the value of radiotherapy in the management carcinoma of the prostate. Br J Urol 36: 535

    Article  PubMed  CAS  Google Scholar 

  • Carlton CJ, Dawoud F, Hudgins P, Scott RJ (1972) Irradiation treatment of carcinoma of the prostate: a preliminary report based on 8 years of experience. J Urol 108: 924–927

    PubMed  Google Scholar 

  • Cox RS, Kaplan ID, Bagshaw MA (1994) Prostate-specific antigen kinetics after external beam irradiation for carcinoma of the prostate. Int J Radiat Oncol Biol Phys 28: 23–31

    Article  PubMed  CAS  Google Scholar 

  • Flocks RH, Kerr HD, Elkins HB, Culp D (1952) Treatment of carcinoma of the prostate by interstitial radiation with radioactive gold (Au198): a preliminary report. J Urol 68: 510

    PubMed  CAS  Google Scholar 

  • Gehan EA (1965) A generalized Wilcoxon test for comparing arbitrarily singly-censored samples. Biometrika 52: 203

    PubMed  CAS  Google Scholar 

  • Hancock SL, Cox RS, Bagshaw MA (1995) Prostate specific antigen after radiotherapy for prostate cancer: a re-evaluation of long term biochemical control and the kinetics of recurrence in patients treated at Stanford. J Urol 154: 1412–1417

    Article  PubMed  CAS  Google Scholar 

  • Hilaris BS, Whitmore WF, Grabstald H, O’Kelly PJ (1972) Radical radiation therapy of cancer the prostate: a new approach using interstitial and external sources. Clin Bull 2: 94

    Google Scholar 

  • Hultberg S (1946) Results of treatment with radiotherapy in carcinoma of the prostate. Acta Radiol 27: 339

    Article  PubMed  CAS  Google Scholar 

  • Kaplan ID, Cox RS, Bagshaw MA (1991) A model of prostatic carcinoma tumor kinetics based on prostate specific antigen levels after radiation therapy. Cancer 68: 400–405

    Article  PubMed  CAS  Google Scholar 

  • Kaplan ID, Cox RS, Bagshaw MA (1993) Prostate specific antigen after external beam radiotherapy for prostatic cancer: follow-up. J Urol 149: 519–522

    PubMed  CAS  Google Scholar 

  • Lai PP, Pilepich MV, Krall JM, et al. (1991) The effect of overall treatment time on the outcome of definitive radiotherapy for localized prostate carcinoma: the Radiation Therapy Oncology Group 75–06 and 77–06 experience. Int J Radiat Oncol Biol Phys 21: 925–933

    Article  PubMed  CAS  Google Scholar 

  • Laramore GE, Krall JM, Thomas FJ, Griffin TW, Maor MH, Hendrickson FR (1985) Fast neutron radiotherapy for locally advanced prostate cancer: results of an RTOG randomized study. Int J Radiat Oncol Biol Phys 11: 1621–1627

    Article  PubMed  CAS  Google Scholar 

  • Mellinger GT, Gleason D, Bailar J, 3rd (1967) The histology and prognosis of prostatic cancer. J Urol 97: 331–337

    PubMed  CAS  Google Scholar 

  • Paschkis R, Tittinger W (1910) Radiumbehandlung eines Prostatasarkoms. Wein Klin Wochenschr 48

    Google Scholar 

  • Pasteau O (1911) Traiment du cancer de la prostate par le radium. Revue des Maladies de la Nutrition 363

    Google Scholar 

  • Pistenma DA, Bagshaw MA, Freiha FS (1979) Extended-field radiation therapy for prostatic adenocarcinoma: status report of a limited prospective trial. In: Johnson DE, Samuels ML (eds) Cancer of the genitourinary tract. Raven Press, New York, pp 229–247

    Google Scholar 

  • Roach M 3rd, Marquez C, Yuo HS, et al. (1994) Predicting the risk of lymph node involvement using the pretreatment prostate specific antigen and Gleason score in men with clinically localized prostate cancer. Int J Radiat Oncol Biol Phys 28: 33–37

    Article  PubMed  Google Scholar 

  • Shipley WU, Tepper JE, Prout GJ, et al. (1979) Proton radiation as boost therapy for localized prostatic carcinoma. JAMA 241: 1912–1915

    Article  PubMed  CAS  Google Scholar 

  • Stamey TA, Ferrari MK, Schmid HP (1993) The value of serial prostate specific antigen determinations 5 years after radiotherapy: steeply increasing values characterize 80% of patients. J Urol 150: 1856–1859

    PubMed  CAS  Google Scholar 

  • Syed AM, Puthawala A, Tansey LA, et al. (1983) Management of prostate carcinoma. Combination of pelvic lymphadenectomy, temporary Ir-192 implantation, and external irradiation. Radiology 149: 829–833

    PubMed  CAS  Google Scholar 

  • von Essen CF, Bagshaw MA, Bush SE, Smith AR, Kligerman MM (1987) Long-term results of pion therapy at Los Alamos. Int J Radiat Oncol Biol Phys 13: 1389–1398

    Article  Google Scholar 

  • Widman BP (1934) Cancer of the prostate. The results of ra- dium and roentgen-ray treatment. Radiology 22: 153

    Google Scholar 

  • Woo S, Kaplan I, Roach M, Bagshaw M (1988) Formula to estimate risk of pelvic lymph node metastasis from the total Gleason score for prostate cancer (letter to the editor). J Urol 140: 387

    PubMed  CAS  Google Scholar 

  • Young HH, Fronz WA (1917) Some new methods in the treatment of carcinoma of the lower genitourinary tract with radium. J Urol 1: 505

    Google Scholar 

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© 1996 Springer-Verlag Berlin Heidelberg

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Bagshaw, M.A., Cox, R.S., Hancock, S.L. (1996). External Beam Radiotherapy for Localized Prostatic Cancer at Stanford: Update at the 38th Year. In: Petrovich, Z., Baert, L., Brady, L.W. (eds) Carcinoma of the Prostate. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60956-5_17

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  • DOI: https://doi.org/10.1007/978-3-642-60956-5_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64627-0

  • Online ISBN: 978-3-642-60956-5

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