Abstract
Paul Ehrlich, the father of “Molecular Pharmacology”, formulated a strategy of chemotherapy based on designing toxic agents containing binding sites that specifically complex with receptor sites present in the parasite or cell type which is to be attacked (Ehrlich, 1890). Only within the past few years, however, has it become apparent that for certain drugs, including agents closely related structurally to some of the dyestuffs tested by Ehrlich, the cellular receptor site is DNA. One of these compounds is the subject of this report.
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Weinstein, I.B., Hirschberg, E. (1971). Mode of Action of Miracil D. In: Hahn, F.E. (eds) Proceedings of the Research Symposium on Complexes of Biologically Active Substances with Nucleic Acids and Their Modes of Action. Progress in Molecular and Subcellular Biology, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65141-0_19
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