Abstract
In a light-microscopic study of the myopathy induced by corticosteroid treatment, ELLIS (92, 93) described an early segmental swelling of the muscle fibres accompanied by varying degrees of eosinophilia of the sarcoplasm. Since histochemical techniques were not used, predilective involvement of one or the other type of muscle fibres could not be demonstrated. Even under prolonged treatment, when severe changes were present in skeletal muscle, the myocardium appeared to be unchanged. Infiltration with fat and focal necrosis were found in the liver. The alterations in skeletal muscle were those of a primary myopathy and were fully reversed when treatment was discontinued.
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© 1975 Springer-Verlag Berlin · Heidelberg
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Heene, R. (1975). Experimental Myopathies. In: Experimental Myopathies and Muscular Dystrophy. Schriftenreihe Neurologie — Neurology Series, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66200-3_2
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DOI: https://doi.org/10.1007/978-3-642-66200-3_2
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-66202-7
Online ISBN: 978-3-642-66200-3
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