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Pharmacology of Drugs Used in Treatment of Acute Gout

  • Chapter
Uric Acid

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 51))

Abstract

Once the diagnosis of acute gout is made, treatment is generally simple and straightforward. Acute gout is probably the most easily treated of the arthritides, provided that therapy is begun early. Most agents effective in controlling acute gouty inflammation have been in use for years and are well known; several new agents have recently become available (Wallace, 1975). A number of reports on the treatment of acute gout have been published (Goldfinger, 1971; Wallace, 1972; Wyngaarden and Kelley, 1976). Table 1 lists the major drugs that have been used for this purpose in clinical practice. The pharmacology and mechanisms of action of these drugs are less well appreciated, however, and deserve further emphasis, although a series of reviews of the clinical pharmacology of one of these agents, colchicine, has previously been reported (Wallace, 1961, 1965; Wallace and Ertel, 1969; Wallace, 1974). Much new recent information has become available.

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Authors
  1. S. L. Wallace
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  2. N. H. Ertel
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Editors and Affiliations

  1. Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor, MI, 48109, USA

    William N. Kelley MD (Professor and Chairman) (Professor and Chairman)

  2. Department of Pathology, Upstate Medical Center, Syracuse, NY, 13210, USA

    Irwin M. Weiner MD (Professor and Chairman) (Professor and Chairman)

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Wallace, S.L., Ertel, N.H. (1978). Pharmacology of Drugs Used in Treatment of Acute Gout. In: Kelley, W.N., Weiner, I.M. (eds) Uric Acid. Handbook of Experimental Pharmacology, vol 51. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66867-8_23

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  • DOI: https://doi.org/10.1007/978-3-642-66867-8_23

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