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Opioide — das Beispiel Fentanyl

  • Chapter
Aufwachraum — Aufwachphase

Part of the book series: Klinische Anästhesiologie und Intensivtherapie ((KAI,volume 24))

Zusammenfassung

Pharmakokinetische Analysen stehen bei Anästhesisten hoch im Kurs, versprach (und verspricht) man sich davon doch eine Verbesserung sowohl der Narkoseführung als auch der Abschätzung postoperativer Gefahren. Hinsichtlich der Opiate müssen heute jedoch zwei Erfahrungen diese Begeisterung dämpfen:

  • — Zum einen halten sich die wenigsten Patienten an vorausberechnete Werte (Problem der biologischen Variabilität),

  • — zum anderen korrelieren die meßtechnisch relativ einfach zugänglichen Blutkonzentrationen nur selten direkt mit dem zentral vermittelten Effekt (Problem der Rezeptortheorie).

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Authors
  1. K. A. Lehmann
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  2. D. Daub
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Editor information

Editors and Affiliations

  1. Zentrum für Anästhesiologie, der Universität Ulm, Steinhövelstraße 9, D-7900, Ulm(Donau), Deutschland

    Friedrich Wilhelm Ahnefeld

  2. Instituts für Anaesthesiologie (Blutzentrale), Allgemeinen öffentlichen Krankenhauses Linz, A-4020, Linz(Donau), Deutschland

    Hans Bergmann (Vorstand) (Vorstand)

  3. Abteilung Chirurgie III, der Universität Ulm, Steinhövelstraße 9, D-7900, Ulm(Donau), Deutschland

    Caius Burri

  4. Zentrum für Anästhesiologie, der Universität Ulm, Prittwitzstraße 43, D-7900, Ulm(Donau), Deutschland

    Wolfgang Dick

  5. Institut für Anaesthesiologie des Klinikums, der Johannes Gutenberg-Universität Mainz, Langenbeckstraße 1, D-6500, Mainz(Rhein), Deutschland

    Miklos Halmágyi

  6. Institut für Anaesthesiologie, Universitätsspital Zürich, Rämistraße 100, CH-8091, Zürich, Schweiz

    Georg Hossli

  7. Institut für Anaesthesiologie, der Universität Erlangen-Nürnberg, Maximiliansplatz 1, D-8520, Erlangen, Deutschland

    Erich Rügheimer (Direktor) (Direktor)

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Lehmann, K.A., Daub, D. (1982). Opioide — das Beispiel Fentanyl. In: Ahnefeld, F.W., et al. Aufwachraum — Aufwachphase. Klinische Anästhesiologie und Intensivtherapie, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68309-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-68309-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-11112-2

  • Online ISBN: 978-3-642-68309-1

  • eBook Packages: Springer Book Archive

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