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Antihypoxischer Effekt von Gallopamil am Gehirn

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Gallopamil

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Zusammenfassung

Über die vasodilatatorischen Eigenschaften von Verapamil und Gallopamil in der Peripherie liegen zahlreiche Arbeiten vor; einige Untersuchungen sind auch an zerebralen Gefäßen — überwiegend In-vitro-Studien an Basilararterienstreifen — durchgeführt worden (Übersicht bei Flaim 1982). Vlahov u. Enzenross beschrieben 1973 eine Hemmung der durch pH-Erniedrigung ausgelösten Konstriktion der Piagefäße an Katzen in vivo durch lokal verabreichtes Gallopamil (D 600) in Konzentrationen ab 1 mg/1. Demgegenüber sind Wirkungen von Verapamil und Gallopamil auf metabolische Reaktionen im Gehirn bisher nicht untersucht worden.

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Authors
  1. A. G. B. Kovách
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  2. E. Dora
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  3. A. Koller
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Editor information

Editors and Affiliations

  1. Abteilung für Kardiologie Zentrum der Inneren Medizin, Klinikum der J.W. Goethe-Universität, Theodor-Stern-Kai 7, D-6000, Frankfurt/Main 70, Deutschland

    Martin Kaltenbach  & Rüdiger Hopf  & 

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© 1983 Springer-Verlag Berlin Heidelberg

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Kovách, A.G.B., Dora, E., Koller, A. (1983). Antihypoxischer Effekt von Gallopamil am Gehirn. In: Kaltenbach, M., Hopf, R. (eds) Gallopamil. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69073-0_7

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  • DOI: https://doi.org/10.1007/978-3-642-69073-0_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-12381-1

  • Online ISBN: 978-3-642-69073-0

  • eBook Packages: Springer Book Archive

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