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New Research Techniques for Studying the Functional Anatomy of Depression

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The Origins of Depression: Current Concepts and Approaches

Part of the book series: Dahlem Workshop Reports Life Sciences Research Report ((DAHLEM LIFE,volume 26))

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Abstract

The brain, the chief target organ for psychiatry, has up to now been studied through approaches that were necessarily indirect. Blood, urine, and cerebrospinal fluid, though valuable indicators of neurochemical and neuropharmacological activity, are removed in time and place from the disordered thought and diluted by the products of both functional and dysfunctional systems. New technologies are now making possible a specific regional approach to patients with the major psychoses. These include 133 Xe blood flow, EEG and evoked potential topography, X-ray transmission scanning (CAT or CT Scans), nuclear magnetic resonance (NMR) imaging, and positron emission tomography (PET). These techniques so far have been more widely applied in schizophrenia than in affective illness, but competing regional hypotheses in dicate the need to apply these new regional approaches in depression.

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Authors and Affiliations

  1. Dept. of Psychiatry Med. Sci. I, University of California, Irvine, CA, 92717, USA

    M. S. Buchsbaum

  2. Section on Clinical Psychophysiology, Biological Psychiatry Branch, National Institute of Mental Health, Bldg 10, Room 4N-317, Bethesda, MD, 25205, USA

    H. H. Holcomb

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  1. M. S. Buchsbaum
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J. Angst

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© 1983 Berlin, Heidelberg, New York, Tokyo: Springer-Verlag.

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Buchsbaum, M.S., Holcomb, H.H. (1983). New Research Techniques for Studying the Functional Anatomy of Depression. In: Angst, J. (eds) The Origins of Depression: Current Concepts and Approaches. Dahlem Workshop Reports Life Sciences Research Report, vol 26. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69129-4_17

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  • DOI: https://doi.org/10.1007/978-3-642-69129-4_17

  • Publisher Name: Springer, Berlin, Heidelberg

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