Abstract
Historically a number of important questions have dominated the field of dementia research in the last decades. Is aging a pathological process? Is dementia accelerated aging? What role does vascular insufficiency play in the process of senility? The clinical physiologists have attempted to answer some of these questions by measurement of cerebral blood flow and most recently concurrent measurement of cerebral energy metabolism. The main advances, however, have come from the neuropathologists, who have demonstrated the quantitative and qualitative differences between normally aging brains and those of demented patients. They have also pointed out that the vast majority of the dementias are due to Alzheimer’s disease, a degenerative process of unknown cause, rather than cerebrovascular disease.
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Frackowiak, R.S.J. (1986). The Significance of Regional Cerebral Blood Flow and Metabolism for Processes of Aging and Dementia. In: Häfner, H., Moschel, G., Sartorius, N. (eds) Mental Health in the Elderly. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70958-6_16
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DOI: https://doi.org/10.1007/978-3-642-70958-6_16
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