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Arterielle Hypertonie - Aktuelle Probleme und Aufgaben

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Hochdruck und Sport
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Zusammenfassung

Unter den derzeit aktuellen Problemen auf dem Gebiet der Behandlung der Hypertonie möchte ich auf folgende Fragen näher eingehen:

  • Soll die sog. milde Hypertonie behandelt werden?

  • Welche Medikamente sind für die Behandlung der milden Hypertonie geeignet?

  • Besitzen β-Rezeptorenblocker eine „kardioprotektive“ Wirkung?

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Literatur

  1. Helgeland A (1980) Treatment of mild hypertension: a five year controlled drug trial. The Oslo study. Amer J Med 69: 725

    Article  PubMed  CAS  Google Scholar 

  2. Management Committee The Australian therapeutic trial in mild hypertension. Lancet 1980/1: 1261

    Google Scholar 

  3. Medical Research Council Working Party (1985) MRC trial of treatment of mild hypertension: principal results. Brit Med J 291: 97

    Article  Google Scholar 

  4. Society of Actuaries (1972) Build and Blood Pressure Study. Society of Actuaries, Chicago (1959)

    Google Scholar 

  5. Dawber TR, Kannel WB (1972) Current status of coronary prevention. Prev Med 1: 499

    Article  PubMed  CAS  Google Scholar 

  6. Veterans Administration Cooperative Study Group on Antihypertensive Agents (1967) Effects of treatment on morbidity in hypertension. Results in patients with diastolic blood pressures averaging 115 through 129 mmHg. J Amer med Ass 202: 1028

    Google Scholar 

  7. Veterans Administration Cooperative Study Group on Antihypertensive Agents (1970) Effects of treatment on morbidity in hypertension. II. Results in patients with diastolic blood pressure averaging 90 through 114 mmHg. J Amer med Ass 213: 1143

    Google Scholar 

  8. Management Committee of the Australian Therapeutic Trial (1982) Untreated mild hypertension. Lancet 1: 185

    Google Scholar 

  9. Freis ED (1982) Should mild hypertension be treated? New Engl. J Med 307: 306

    Article  PubMed  CAS  Google Scholar 

  10. Smith WM (1977) Treatment of mild hypertension. Results of a ten-year intervention trial. US- Public Health Service Hospital Cooperative Study Group. Circ. Res., 40 (Suppl I), 98

    Google Scholar 

  11. Hypertension Detection and Follow-up Programm Cooperative Group (1979) Five-year findings of the hypertension detection and follow-up program. I. Reduction in mortality of persons with high blood pressure, including mild hypertension. J Amer med Ass 242: 2562

    Google Scholar 

  12. Hypertension Detection and Follow-up Program Cooperative Group (1982) The effect of treat-ment on mortality in „mild“ hypertension. New Engl J Med 307: 976

    Article  Google Scholar 

  13. Hypertension Detection and Follow-up Programm Cooperative Group (1982) Five-year findings of the hypertension detection and follow-up programm. III. Reduction in stroke incidence among persons with high blood pressure. J Amer med Ass 247: 633

    Article  Google Scholar 

  14. Multiple Risk Factor Intervention Trial Research Group (1982) Multiple Risk Factor Interven-tion Trial. Risk factor changes and mortality results. J Amer med Ass 248: 1465

    Google Scholar 

  15. Guidelines for the treatment of mild hypertension (1983) memorandum from a WHO/ISH meeting. Lancet 1: 457

    Google Scholar 

  16. Wilkinson PR, Hesp R, Issler H, Raftery EB (1975) Total-body and serum potassium during prolonged thiazide therapy for essential hypertension. Lancet I: 759

    Article  Google Scholar 

  17. Heimsoth V und Hartmann F (1965) Untersuchungen zur Störung des Harnsäurestoffwechsels nach Saluretica-Verabreichung. Dtsch Med Wschr 43: 1905

    Article  Google Scholar 

  18. Distler A, Keim JH, Philipp Th, Walter U (1975) Blutdrucksenkende Wirkung von Spironolac-tone und von Butizid bei Patienten mit essentieller Hypertonie und niedrigem sowie mit norma-lem Plasmarenin. Therapiewoche 25: 3039

    Google Scholar 

  19. Jahnecke J (1973) Diabetogene Nebenwirkungen der Pharmakotherapie. Med Klin 68: 1046

    PubMed  CAS  Google Scholar 

  20. Lewis PJ, Kohner EM, Petrie A, Dollery CT (1976) Deterioration of glucose tolerance in hyper-tensive patients on prolonged diuretic treatment. Lancet 1: 564

    Article  PubMed  CAS  Google Scholar 

  21. Murphy MB, Kohner E, Lewis PJ et al (1982) Glucose intolerance in hypertensive patients treated with diuretics; a fourteen-year follow-up. Lancet II: 1293

    Article  Google Scholar 

  22. Amery A, Bulpitt C, Schaepdryver de A et al (1978) Glucose intolerance during diuretic therapy. Results of trial by the European Working Party on Hypertension in the Elderly. Lancet I: 681

    Article  Google Scholar 

  23. Ames RP, Hill P (1976) Elevation of serum lipid levels during diuretic therapy of hypertension. Am J Med 61: 748

    Article  PubMed  CAS  Google Scholar 

  24. Grimm RH, Leon AS, Hunningh ake DB et al (1981) Effects of thiazide diuretics on plasma li-pids and lipoproteins in mildly hypertensive patients. Ann Int Med 94: 7

    PubMed  Google Scholar 

  25. Schnaper H, Fitz A, Fröhlich E et al (1977) Chlorthalidone and serum cholesterol. Lancet II: 295

    Article  Google Scholar 

  26. Glück Z, Baumgartner G, Weidmann P et al (1978) Increased ratio between serum ß- and α-li-poproteins during diuretic therapy: an adverse effect? Clin Sei Mol Med 55: 325s

    Google Scholar 

  27. Glück Z, Weidmann P, Mordasini R et al (1980) Increased serum low-density lipoprotein cholesterol in men treated short-term with the diuretic chlorthalidone. Metabolism 29: 240

    Article  PubMed  Google Scholar 

  28. Valimäki M, Harno K und Nikkilä EA (1983) Serum lipoproteins and indices of glucose tolerance during diuretic therapy: a comparison between hydrochlorothiazide and piretanide. J Cardiovasc Pharmacol 5: 525

    Article  PubMed  Google Scholar 

  29. Medical Research Council Working Party on Mild to Moderate Hypertension (1983) Ventricular extrasystoles during thiazide treatment: Substudy of MRC mild hypertension trial. Br Med J 287: 1249

    Google Scholar 

  30. Kaplan NM (1984) Our appropriate concern about hypokalemia. Am J Med 77: 1

    Article  PubMed  CAS  Google Scholar 

  31. Ames RP (1983) Negative effects of diuretic drugs on metabolic risk factors for coronary heart disease: possible alternative drug therapies. Am J Cardiol 51: 632

    Article  PubMed  CAS  Google Scholar 

  32. Berglund G, Sannerstedt R, Andersson O et al (1978) Coronary heart disease after treatment of hypertension. Lancet 1: 1

    Article  PubMed  CAS  Google Scholar 

  33. Materson BJ, Oster JR, Michael UF et al (1978) Dose response to chlorthalidone in patients with mild hypertension. Clin Pharmacol Ther 24: 192

    PubMed  CAS  Google Scholar 

  34. Tweeddale MG, Ogilvie RI, Ruedy J (1977) Antihypertensive and biochemical effects of chlorthalidone. Clin Pharmacol Ther 22: 519

    PubMed  CAS  Google Scholar 

  35. Lohmann FW (1981) Die Beeinflussung des Stoffwechsels durch Beta-Rezeptoren-Blocker. Klin Wochenschr 59: 49

    Article  PubMed  CAS  Google Scholar 

  36. Beta-Blocker Heart Attack Trial Study Group (1981) The Beta-Blocker Heart Attack Trial. J Am Med Assoc, 246: 2073

    Article  Google Scholar 

  37. Norwegian Multicenter Study Group (1981) Timolol-induced reduction in mortality and rein- farction in patients surviving acute myocardial infarction. N Engl J Med 304: 801

    Article  Google Scholar 

  38. Spivack C, Ockens S und Frishman H (1983) Calcium antagonists. Clinical use in the treatment of systemic hypertension. Drugs, 25: 154

    Article  PubMed  CAS  Google Scholar 

  39. The IPPPSH Collaborative Group (1985) Cardiovascular risk and risk factors in a randomized trial of treatment based on the beta-blocker Oxprenolol: the International Prospective Primary Prevention Study in Hypertension (IPPPSH). J Hypertension 3: 379

    Article  Google Scholar 

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© 1986 Springer-Verlag Berlin Heidelberg

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Distler, A. (1986). Arterielle Hypertonie - Aktuelle Probleme und Aufgaben. In: Lohmann, F.W. (eds) Hochdruck und Sport. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71181-7_2

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  • DOI: https://doi.org/10.1007/978-3-642-71181-7_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16531-6

  • Online ISBN: 978-3-642-71181-7

  • eBook Packages: Springer Book Archive

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