Abstract
Inhalation anesthetics undergo biotransformation in humans and they follow the general pathway of breakdown of drugs. Most prominent is the oxidative pathway depdendent on the non-specific microsomal hepatic enzyme system, commonly abbreviated P450. This non-specific system oxidizes xenobiotics and is unique in requiring the presence of di-oxygen (O2) and NADPH. The general reaction of xenobiotics in this system is depicted in Figure 1.
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© 1986 Springer-Verlag Berlin Heidelberg
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Cascorbi, H.F. (1986). Biotransformation of Inhalation Anesthetics. In: List, W.F., Schalk, H.V., Fitzal, S. (eds) Aktueller Stand der klinischen Anaesthesie. Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine, vol 190. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71229-6_2
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DOI: https://doi.org/10.1007/978-3-642-71229-6_2
Publisher Name: Springer, Berlin, Heidelberg
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