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Peripheres Nervensystem und AIDS

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AIDS und Nervensystem

Zusammenfassung

Das vielgestaltige Vollbild der HIV-Infektion, das eigentliche „acquired immune deficiency Syndrome“ (AIDS), ist durch opportunistische Infektionen und bösartige Tumoren gekennzeichnet, die für den infausten Verlauf der Erkrankung verantwortlich sind. Dabei wird die klinische Symptomatik weniger von erreger- oder tumorspezifischen Eigenschaften bestimmt, als durch die Lokalisation und pathogenetischen Folgen der einzelnen Komplikationen, die durch die geschwächte Immunabwehr auftreten. Aufgrund seiner engen anatomischen und funktionellen Zusammenhänge gilt dies auch besonders für das Nervensystem, dessen Beteiligung erheblich zur Morbidität und Mortalität bei AIDS beiträgt. Neben sekundären begleitenden Erkrankungen des Nervensystems konnte in letzter Zeit auch ein primärer Befall des zentralen (Shaw et al. 1985) und peripheren (Ho et al. 1985) Nervensystems durch das „human immunodeficiency virus“ (HIV) gezeigt werden. Die möglichen Wirkungen des HIV am Nervensystem in den verschiedenen Krankheitsstadien sind Gegenstand intensiver Forschung, bei denen auch die gleichzeitige Beteiligung anderer Erreger, z.B. des Zytomegalovirus, zu berücksichtigen ist.

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Authors
  1. H. J. Möbius
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  2. W. Schlote
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  3. W. Enzensberger
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Editor information

Editors and Affiliations

  1. Abteilung für Neurologie Zentrum der Neurologie und Neurochirurgie, Klinikum der J.W. Goethe-Universität Frankfurt, Schleusenweg 2-16, D-6000, Frankfurt 71, Germany

    Peter-A. Fischer

  2. Neurologisches Institut (Edinger Institut), Klinikum der J.W. Goethe-Universität Frankfurt, Deutschordenstraße 46, D-6000, Frankfurt 71, Germany

    Wolfgang Schlote

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© 1987 Springer-Verlag Berlin Heidelberg

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Möbius, H.J., Schlote, W., Enzensberger, W. (1987). Peripheres Nervensystem und AIDS. In: Fischer, PA., Schlote, W. (eds) AIDS und Nervensystem. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72674-3_8

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  • DOI: https://doi.org/10.1007/978-3-642-72674-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-17820-0

  • Online ISBN: 978-3-642-72674-3

  • eBook Packages: Springer Book Archive

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