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Transplantation: Wherefore So Slight an Impact?

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Uremia Therapy
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Abstract

The management of end stage renal disease (ESRD) has a major socioeconomic impact upon health care delivery in the Western world. Between 30 and 79 new cases per million population are accepted annually for care [1–3], this almost certainly reflecting an underestimate of the incidence of ESRD within the population [4]. Direct costs of such support have risen dramatically within the past decade, such that the expenditure on this therapy alone now exceeds 2 billion dollars annually in the United States.

Supported in part by grants from the Medical Research Council of Canada, the Ivey Foundation, and the Kidney Foundation of Canada. Dr. P. A. Keown is a Career Scientist of the Ontario Ministry of Health.

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References

  1. Kramer P, Broyer M, Brunner FP et al (1984) In: Davison AM (ed) Combined report on regular dialysis and transplantation in Europe XIV, 1983, vol 21

    Google Scholar 

  2. Posen G A (1984) All patients and facilities. Canadian renal failure register. The Kidney Foundation of Canada, p 5

    Google Scholar 

  3. Schmidt RW, Blumenkrantz M, Wiegmann TB (1983) The dilemmas of patient treatment for end stage renal disease. Am J Kidney Dis 3:37

    PubMed  CAS  Google Scholar 

  4. Vital Statistics of the United States, vol 2, mortality part A (1965, 1966,1968)

    Google Scholar 

  5. Keown PA, Stiller CR (1986) Control of rejection of transplanted organs. In: Stollerman GH (ed) Advances in internal medicine. Yearbook Medical, Chicago, pp 17–46

    Google Scholar 

  6. Keown PA, Stiller CR, Wallace AC (1986) The nephrotoxicity of cyclosporine A. Kidney transplant rejection: diagnosis and treatment. Dekker, New York, pp 423–457

    Google Scholar 

  7. The Canadian Multicentre Transplant Study Group (1986) A randomized Clinical trial of cyclosporine in cadaveric renal transplantation. Analysis at three years. N Engl J Med 314:1219

    Article  Google Scholar 

  8. Sinclair NR, Jeffery JR, Keown PA, Stiller CR (1986) Risk factors and HLA Matching in renal transplantation using cyclosporine therapy. Transplant Proc (to be published)

    Google Scholar 

  9. Evans RW, Manninen DL, Garrison LP Jr., Hart LG et al (1985) The quality of life of patients with end stage renal disease. N Engl J Med 312:553

    Article  PubMed  CAS  Google Scholar 

  10. Robinette MA, Marshall WJ, Arbus GS et al (1985) The donation process. Transplant Proc XVII:45

    Google Scholar 

  11. Bart KJ, Macon EJ, Whittier FC et al (1981) Cadaveric kidneys for transplantation: a paradox of shortage in the face of plenty. Transplantation 31:379

    Article  PubMed  CAS  Google Scholar 

  12. Carlson D, Hellerstedt W, Anderson J et al (1985) Kidney donor candidacy study. Transplant Proc XVII: 99

    Google Scholar 

  13. Cardella CJ, DeVeber GA, Hollenberg C et al (1985) Donor identification. Transplant Proc XVII, 35

    Google Scholar 

  14. Hutchinson TA, Thomas DC, Lemieux JC et al (1984) Prognostically controlled comparison of dialysis and renal transplantation. Kidney Int 26:44

    Article  PubMed  CAS  Google Scholar 

  15. Smith MD, Hong BA, Michelman JE (1983) Treatment bias in the management of end stage renal disease. Am J Kidney Dis 3:21

    PubMed  CAS  Google Scholar 

  16. Robinette MA, Stiller CR (1985) Summary of task force recommendations. Transplant Proc XVII: 13

    Google Scholar 

  17. Keown PA, Stiller CR (1986) Dialysis or transplantation: an integrated approach to Management of end stage kidney disease. Kidney Int (to be published)

    Google Scholar 

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© 1987 Springer-Verlag Berlin Heidelberg

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Keown, P.A., Stiller, C.R. (1987). Transplantation: Wherefore So Slight an Impact?. In: Gurland, H.J. (eds) Uremia Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72720-7_7

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  • DOI: https://doi.org/10.1007/978-3-642-72720-7_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72722-1

  • Online ISBN: 978-3-642-72720-7

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