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Pathophysiologie — Vasopressin-System

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Herzinsuffizienz

Part of the book series: Aktuelle Therapieprinzipien in Kardiologie und Angiologie ((THERAPIEPRINZ.))

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Zusammenfassung

Bis zu 33% aller Patienten mit Herzinsuffizienz weisen erhöhte Vasopressinspiegel im Plasma auf. Ein für eine vorhegende Osmolalität erhöhtes Vasopressin wird durch ACE-Hemmer normalisiert. Die hämodynamische Bedeutung erhöhter Vasopressinspiegel ist allerdings noch nicht klar. Die Anwendung eines vaskulären Vasopressinantagonisten zeigte — bei einer geringen Patientenzahl mit erhöhtem Vasopressinspiegel — eine Verbesserung der Hämodynamik mit Abnahme des Gefäßwiderstandes und Zunahme des Herzzeitvolumens. Um die Bedeutung von Vasopressin abschließend beurteilen zu können, sind Untersuchungen an größeren Kollektiven notwendig.

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  1. K. J. Osterziel
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  1. Abt. Innere Medizin III, Med. Klinik, Bergheimer Straße 58, D-6900, Heidelberg, Deutschland

    Rainer Dietz

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© 1992 Springer-Verlag Berlin Heidelberg

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Osterziel, K.J. (1992). Pathophysiologie — Vasopressin-System. In: Dietz, R. (eds) Herzinsuffizienz. Aktuelle Therapieprinzipien in Kardiologie und Angiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77021-0_10

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  • DOI: https://doi.org/10.1007/978-3-642-77021-0_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-54670-2

  • Online ISBN: 978-3-642-77021-0

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