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Pathogenese der Endometriose und Wirkungsmechanismus der Hormontherapie

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Leuprorelinacetat — Ein neues GnRH-Analogon

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Zusammenfassung

Die Endometriose ist eine Erkrankung von Frauen im reproduktiven Alter. Unter Endometriose versteht man die Heterotopie von Gebärmutterschleimhaut. Ektopes endometriotisehes Gewebe unterscheidet sich morphologisch jedoch erheblich von eutoper Schleimhaut (Schweppe u. Wynn 1984; Schweppe et al. 1981), so ist beispielsweise die Konzentration von Steroidrezeptoren im Zytosol der Zellen aus Endometrioseherden insgesamt niedriger und außerdem weit weniger zyklusabhängig. Endometriotisehes Gewebe — obwohl geschlechtshor- monabhängig — reagiert nicht immer genauso wie Endometrium auf Hormonzufuhr oder -entzug.

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Authors
  1. L. Kiesel
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  2. B. Runnebaum
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Editor information

Editors and Affiliations

  1. Voßstraße 9, 6900, Heidelberg, Germany

    Benno Runnebaum (Ärztlicher Direktor der Abteilung für Gynäkologische Endokrinologie und Fertilitätsstörungen der Universitäts-Frauenklinik Heidelberg) (Ärztlicher Direktor der Abteilung für Gynäkologische Endokrinologie und Fertilitätsstörungen der Universitäts-Frauenklinik Heidelberg)

  2. Klinikum der Albert-Ludwigs-Universität, Hugstetter Straße 55, 7800, Freiburg, Germany

    Meinert Breckwoldt (Direktor der Universitäts-Frauenklinik) (Direktor der Universitäts-Frauenklinik)

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© 1992 Springer-Verlag Berlin Heidelberg

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Kiesel, L., Runnebaum, B. (1992). Pathogenese der Endometriose und Wirkungsmechanismus der Hormontherapie. In: Runnebaum, B., Breckwoldt, M. (eds) Leuprorelinacetat — Ein neues GnRH-Analogon. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77666-3_2

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  • DOI: https://doi.org/10.1007/978-3-642-77666-3_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55721-0

  • Online ISBN: 978-3-642-77666-3

  • eBook Packages: Springer Book Archive

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