Skip to main content

Regulation der sekretorischen IgA-Antwort im Darm

  • Conference paper
Ökosystem Darm IV

Zusammenfassung

Der Darm stellt die größte Kontaktfläche des Körpers mit antigenem Material dar. Ein redundantes Barrieresystem steht dem gegenüber.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Alverdy JC, Aoys E, Moss GS (1988) Total parenteral nutrition promotes bacterial translocation from the gut. Surgery 104: 185

    PubMed  CAS  Google Scholar 

  2. Alverdy JC, Weiss A, Carrington P, Aoys E (1990) The effect — of total parenteral nutrition on gut lamina propria plasma cells. JPEN 14 [Supp1]: 8

    Article  Google Scholar 

  3. Arizono N, Matsuda S, Hattori T, Kojiina Y, Maeda T, Galli S (1990) Anatomical variation in mast cell nerve association in the rat small intestine, heart, lung and skin. Lab Invest 62 /5: 626

    PubMed  CAS  Google Scholar 

  4. Bienenstock J, Befus AD (1980) Mucosal immunology. Immunology 41: 249

    PubMed  CAS  Google Scholar 

  5. Brandtzaeg P (1985) Role of J chain and secretory component in receptor-mediated glandular and hepatic transport of immunoglobulins in man. Scand J Immunol 22: 111

    CAS  Google Scholar 

  6. Brandtzaeg P, Sollid LM, Thraue PS, Kuale DS, Bjerke K, Scott H, Kett K, Rognum TO (1988) Lymphoepithelial interactions in the mucosal immune system. Gut 29: 1116

    Article  PubMed  CAS  Google Scholar 

  7. Brandtzaeg P, Bjerke K (1990) Immunomorphological chracteristic of human Peyer’s patches. Digestion 46 [Suppl 2]: 262

    Article  PubMed  Google Scholar 

  8. Brandtzaeg P, Halstensen TS, Hutifeldt HS, Krajci P, Kvale D, Scott H, Thrane PS (1992) Epithelial expression of HLA, secretory component (poly Ig-receptor) and adhesion molecules in the human alimentary tract. Ann N Y Acad Sci (in press)

    Google Scholar 

  9. Burke DJ, Alverdy JC, Moss GS (1989) Glutamine-supplemented total parenteral nutrition improves gut immune function. Arch Surg 124: 1396

    PubMed  CAS  Google Scholar 

  10. Butcher EC, Scolly RG, Weissman JC (1980) Organ specificity of lymphocyte migration: mediations by highly selective lymphocyte interaction with organ specific determinats on HEV. Eur J Immunol 10: 556

    Article  PubMed  CAS  Google Scholar 

  11. Cebra JJ et al. (1977) The secretory IgA system of the gut. In: Immunology of the gut. Ciba foundation symposium 46, pp 5–28

    Google Scholar 

  12. Chase MW (1946) Inhibition of experimental drug allergy by prior feeding of the sensitizing agent. Proc Soc Exp Biol Med 61: 257

    PubMed  CAS  Google Scholar 

  13. Danek A, O ‘Dorisio SM, O’Dorisio TM, George TM (1983) Specific binding sites for vasoactive intestinal polypeptide on nonadherent peripheral blood lymphocytes. J Immunol 131: 1173

    PubMed  CAS  Google Scholar 

  14. Delacroix DL, Vaerman JP (1983) Function of the human liver in IgA homeostasis in plasma. Ann N Y Acad Sci 409: 383

    Article  PubMed  CAS  Google Scholar 

  15. Dimitriadon V, Buzzi MG, Moskowitz MA, Theoharides TC (1991) Trigeminal sensory, fiber stimulation induces morphological changes reflecting secretion in rat dura mater mast cells. Neuroscience 44 /1: 97

    Article  Google Scholar 

  16. Enders G, Gottwald T, Brendel W (1986) Induction of oral tolerance in rats without Peyer’s patches. Immunology 58: 311

    PubMed  CAS  Google Scholar 

  17. Ganguly AK, Sathiamoorthy SS, Bhatnagar OP (1978) Effect of subdiaphragmatic vagatomy on astric mucosal mast cell population in pylorus ligated rats. Quart J Exp Physiol 63: 89

    PubMed  CAS  Google Scholar 

  18. Goldblum RM (1990) The role of IgA in local immune protection. J. Clin Immunol 10 (6):64 S

    Google Scholar 

  19. Gottwald T, Späth G, Haas W, Teichmann R (1991) Dysfunction of the mucosa associated lymphoid tissue (sIgA) due to dietary changes. Langenbecks Arch Chir [Suppl]: 469

    Google Scholar 

  20. Guy-Grand D, Griscelli C, Vassalli P (1974) The gut associated lymphoid system: Nature and properties of the large dividing cells. Eur J Immunol 4: 435

    Google Scholar 

  21. Helme RD, Eglezos A, Dandie GW, Andrews PV, Boyd RL (1987) The effect of substance P on the regional lymph node antibody response to antigenic stimulation in capsaicus-pretreated rats. J Immunol 139: 3470

    PubMed  CAS  Google Scholar 

  22. Kerr MA (1990) The structure and function of human IgA. Biochem J 271: 285

    PubMed  CAS  Google Scholar 

  23. Lamm ME (1976) Cellular aspects of IgA. Adv Immunol 22: 223

    Article  PubMed  CAS  Google Scholar 

  24. Lindh E (1974) Increased resistance of immunoglobulins A to proteolytic degradation after binding of secretory component. J Immunol 114284

    Google Scholar 

  25. Mc Nabb PC, Tomasi TB (1981) Host defense mechanismus at the mucosal surface. Ann Rev Microbiol 138: 976

    Google Scholar 

  26. Masson SD, Perdue MH (1990) Changes in distribution of la antigen on epithelium of the jejunum and ileum in rats infected with Nippostrongylus brasiliensis. Chir Immunol Immunopathol 57: 83

    Article  CAS  Google Scholar 

  27. Mayer L, Eisenhardt D, Salomon P, Bauer W, Plons R, Piccimini L (1991) Expression of class II molecules on intestinal epithelial cells in humans; differences between normal and inflammatory bowel disease. Gastroenterology 100: 3

    PubMed  CAS  Google Scholar 

  28. Michetti P, Mohan MJ, Porta N, Blum AL, Krakenbuhl JP, Mekalanos JI, Nentra MR (1992) A single monoclonal IgA is sufficient to prevent polarized MDCK cell monolayer invasion by S.tyhimurium. Gastroenterology 102 [Suppl 4]: A 665

    Google Scholar 

  29. Ottaway CA, Greenberg GR (1984) Interaction of vasoactive intestinal peptide with mouse lymphocytes: specific binding and the modulation of mitogen response. J Immunol 132: 417

    PubMed  CAS  Google Scholar 

  30. Parfrey NA, Prud’Homme GJ (1990) Patterns of MHC antigen modulation in cyclosporine-induced autoimmunity: implications for pathogenesis. Am J Pathol 136: 479

    PubMed  CAS  Google Scholar 

  31. Parrott DMW (1976) The gut as a lymphoid organ. Clin Gastroenterol 5: 211

    PubMed  CAS  Google Scholar 

  32. Rudzik O, Clancy RL, Perey DY, Day RP, Bienenstock J (1975) Repopulation with IgA containing cells of bronchial and intestinal lamina propria after transfer of homologous PP and bronchial lymphocytes. J Immunol 114: 1599

    Google Scholar 

  33. Rush BF, Sori HJ, Murphy TF (1988) Endotoxemia and bacteremia during hemorrhagic shock: the link between trauma and sepsis. Ann Surg 207: 549

    Article  PubMed  Google Scholar 

  34. Späth G, Gottwald T, Haas W, Hohner M (1991) L-Alanyl-L-Glutamin verbessert nicht die durch total parenterale Ernährung beeinträchtigte Barrierefunktion der Darmschleimhaut gegen luminale Mikroorganismen. Langenbecks Arch Chir [Suppl]: 473

    Google Scholar 

  35. Späth G, Berg RD, Specian RD, Deitch EA (1990) Food without fiber promotes bacterial translocation from the gut. Surgery 108: 240

    Google Scholar 

  36. Stanisz AM, Scicchitano R, Dazin P, Bienenstock J, Payan DG (1987) Distribution of substance P receptors on murine spleen and Peyer’s patch T and B cells. J Immunol 139: 749

    PubMed  CAS  Google Scholar 

  37. Stead RH, Bienenstock J, Stanisz AM (1987) Neuropeptide regulation of mucosal immunity. Immunol Rev 100: 333

    Article  PubMed  CAS  Google Scholar 

  38. Stead RH, Dixon MF, Bramwell NH, Riddel RH, Bienenstock J (1989) Mast cells are closely apposed to nerves in the human gastrointestinal mucosa. Gastroenterology 97: 575

    PubMed  CAS  Google Scholar 

  39. Streeter PR, Berg EL, Rouse BTN, Bargatze RF, Butcher EC (1988) A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331: 41

    Article  PubMed  CAS  Google Scholar 

  40. Wilson AD, Bland PW, Stokes CR (1990) Expression and distribution of Ia antigen in the murine small intestine; influence of environment and cholera toxin. Int Arch App! Immunol 91: 348

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Gottwald, T., Teichmann, R., Becker, H.D. (1993). Regulation der sekretorischen IgA-Antwort im Darm. In: Bockemühl, J., Ottenjann, R., Zeitz, M., Lux, G. (eds) Ökosystem Darm IV. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77930-5_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-77930-5_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-56198-9

  • Online ISBN: 978-3-642-77930-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics