Abstract
It has been more than a decade since the description of primate lentiviruses as the etiological agents for immunodeficiencies (Barre—Sinoussi et al. 1983; Gallo et al. 1984; Levy et al. 1984; Clavel et al. 1986). Since that time, besides the human immunodeficiency viruses (HIV-1 and HIV-2), molecular isolates of simian immunodeficiency viruses (SIVs; Desrosiers 1990), as well as related viruses in cattle, cats, sheep, and goats, have been obtained. For HIVs and SIVs, extensive nucleotide sequencing information is available; the sequences from 30 or more individual HIV isolates and 20 or more SIV isolates are available in one recent compilation (Myers et al. 1992a). Based on this information, the phylogenetic relationship between (and among) HIVs and SIVs has been proposed (reviewed in Desrosiers 1990; Myers et al. 1992b). From this perspective, we can operationally categorize the primate lentiviruses into four groups, represented by (a) HIV-1 and SIVcpz; (b) SIVsmm, SIVmac, and HIV-2; (c) SIVagm; and (d) SIVmnd (Desrosiers 1990; Myers et al. 1992b).
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© 1994 Springer-Verlag Berlin Heidelberg
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Jeang, K.T., Gatignol, A. (1994). Comparison of Regulatory Features Among Primate Lentiviruses. In: Letvin, N.L., Desrosiers, R.C. (eds) Simian Immunodeficiency Virus. Current Topics in Microbiology and Immunology, vol 188. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78536-8_7
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