Abstract
Large skin wounds such as in burns lead to significant losses of fluid, electrolytes, and energy and also porvide a portal of entry for infections. Therefore cutaneous wound healing and epithelial coversage is a critical issue in these patients and has led to a number of developments in the field of skin transplantation and skin replacement.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Eriksson E, Liu PY, Zeckel Y, Binder T, Breuing K, Miller DR (1991) In vivo cell culture accelerates reepithelialization. Surg Forum 41:670–673
Breuing K, Eriksson E, Liu PY, Miller DR (1992) Healing of partial thickness porcine skin wounds in a liquid environment. J Surg Res 52:50–58
Billingham RE, Reynolds J (1952) Transplantation studies on sheets of pure epidermal epithelium and on epidermal cell suspensions. Br J Plast Surg 5:25–36
Mackenzie IC, Fusenig NE (1983) Regeneration of organized epithelial structure. J Invest Dermatol 81(1):189s–194s
Worst PKM, Valentine EA, Fusenig NE (1974) Formation of epidermis after reimplantation of pure primary epidermal cell cultures from perinatal mouse skin. JNCI 53(4): 1061–1064
Worst PKM, Mackenzie IC, Fusenig NE (1982) Reformation of organized epidermal structure by transplantation of suspensions and cultures of epidermal and dermal cells. Cell Tissue Res 225
Weinberg WC, Goodman LV, George C, Morgan DL, Ledbetter S, Yuspa SH, Lichti U (1993) Reconstitution of hair follicle development in vivo: determination of follicle formation, hair growth and hair quality by dermal cells. J Invest Dermatol 100:229–236
Morgan JF, Barrandon Y, Green H, Mulligan RC (1987) Expression of an exogenous growth hormone gene by transplantable human epidermal cells. Science 237:1476–1479
Teumer J, Lindahl A, Green H (1990) Human growth hormone in the blood of athymic mice grafted with cultures of growth hormone-secreting human keratinocytes. FASEB J 4:3245–3250
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Vogt, P., Hatzis, D., Thompson, S., Mulligan, R., Andree, C., Eriksson, E. (1995). Keratinocytes Express an Intracellular Marker Gene and Regenerate the Epidermis in Porcine Full-Thickness Wounds After Retroviral Gene Transfer. In: Engemann, R., Holzheimer, R., Thiede, A. (eds) Immunology and Its Impact on Infections in Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79079-9_9
Download citation
DOI: https://doi.org/10.1007/978-3-642-79079-9_9
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-58145-1
Online ISBN: 978-3-642-79079-9
eBook Packages: Springer Book Archive