Abstract
High acetate production and low acetate utilization have been described as metabolic characteristics of malignant tumor metabolism (Bush 1953; Elliot and Greig 1937; Fredman and Graff 1958; Hepp et al. 1966; Katz et al. 1976; Pardee et al. 1959). These observations were made in the murine system. Hepp et al. (1966) described a disequilibrium between the acetate-activating and acetate-inactivating enzymes (acetate thiokinase and acetyl-coenzyme A deacylase respectively) and demonstrated that the inactivation was more pronounced.
The authors thank Mrs. Marlies Braun for excellent technical assistance.
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© 1988 Springer-Verlag Berlin · Heidelberg
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Neumann, H.A., Hermann, D.J.B., Engelhardt, R. (1988). Changes of Plasma Acetate Levels in Whole-Body Hyperthermia. In: Issels, R.D., Wilmanns, W. (eds) Application of Hyperthermia in the Treatment of Cancer. Recent Results in Cancer Research, vol 107. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83260-4_5
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DOI: https://doi.org/10.1007/978-3-642-83260-4_5
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