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Monoclonal Antibodies: Characterization and Diagnosis of Malignant Lymphomas and Other Skin Neoplasms

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Dermatology in Five Continents

Abstract

The development of monoclonal antibody technology by Köhler and Milstein [1] in 1975 revolutionized the use of antibodies as tools in cell biology, immunology, and many branches in medicine, including diagnostic pathology and dermatohistology. The value of antibodies in medicine lies in the fact that they can be used to detect specific molecules in sera and tissue sections. Antibodies have been utilized in tissue sections for this purpose since Coons et al. [2] developed immunofluorescence labelling techniques in 1941.

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References

  1. Köhler G, Milstein C (1975) Nature 256:495–497.

    Article  PubMed  Google Scholar 

  2. Coons AH, Creech HJ, Jones RN (1941) Proc Soc Biol Med 17:200–202.

    Google Scholar 

  3. von Behring E (1890) Dtsch Med Wochenschr 50:1145.

    Google Scholar 

  4. Cordell JL, Falini B, Erber W, Gosh A, Abdulaziz Z, MacDonald S et al. (1984) J Histochem Cytochem 32:219–229.

    Article  PubMed  CAS  Google Scholar 

  5. Stein H, Gatter KG, Asbahr H, Mason DY (1985) Lab Invest 52:676–683.

    PubMed  CAS  Google Scholar 

  6. Erber WN, Mynheer Mason DY (1986) Lancet I:761–765.

    Article  Google Scholar 

  7. Rappaport H (1966) In: Atlas of Tumor Pathology, Sect 3, Fasc 8. Armed Forces Institute of Pathology, Washington, DC.

    Google Scholar 

  8. Lennert K, Stein H, Kaiserling E (1975) Br J Cancer 31:29–43.

    Google Scholar 

  9. Gerard-Marchant R, Hamlin I, Lennert K, Rilke F, Stansfeld AG, van Unnik JAM (1974) Lancet II:406–408.

    Google Scholar 

  10. Lukes RJ, Collins RD (1975) Br J Cancer [Suppl II] 31:1–28.

    Google Scholar 

  11. National Cancer Institute Sponsored Study (1982) Cancer 49:2112–2135.

    Article  Google Scholar 

  12. Rilke F, Lennert K (1981) Histopathology of Non-Hodgkin’s Lymphomas (Based on the Kiel Classification). Springer, Berlin Heidelberg New York, p 112.

    Book  Google Scholar 

  13. Reinherz EL, Kung PC, Goldstein G, Levy RH, Schlossman SF (1980) Proc Nat Acad Sci USA 77:1588–1592.

    Article  PubMed  CAS  Google Scholar 

  14. Greaves MF, Hariri G, Newman RA, Sutherland DR, Ritter MA, Ritz J (1983) Blood 61:628–639.

    PubMed  CAS  Google Scholar 

  15. Stein H, Lennert K, Feller AC, Mason DY (1984) Adv Cancer Res 42:67–147.

    Article  PubMed  CAS  Google Scholar 

  16. Feller AC, Parwaresch MR, Stein H, Ziegler A (1986) Leukem Res 10:1025–1031.

    Article  CAS  Google Scholar 

  17. Stein H, Gerdes J, Kirchner H, Schaadt M, Diehl V (1981) Int J Cancer 28:425–429.

    Article  PubMed  CAS  Google Scholar 

  18. Schwab U, Stein H, Gerdes J, Lemke H, Kirchner H, Schaadt M, Diehl V (1982) Nature 299:65–67.

    Article  PubMed  CAS  Google Scholar 

  19. Stein H, Gerdes J, Schwab U, Lemke H, Mason DY, Ziegler A et al. (1982) Int J Cancer 30:445–459.

    Article  PubMed  CAS  Google Scholar 

  20. Stein H, Mason DY, Gerdes J, O’Conner N, Wainscoat J, Pallesen G, Gatter K, Falini B, Delsol G, Lemke H, Schwarting R, Lennert K (1985) Blood 66:848–858.

    PubMed  CAS  Google Scholar 

  21. Hsu S-M, Yang K, Jaffe ES (1985) Am J Pathol 118:209–217.

    PubMed  CAS  Google Scholar 

  22. Stein H, Gerdes J (1986) Verh Dtsch Ges Path 70:127–299.

    CAS  Google Scholar 

  23. Falini B, Stein H, Ribacchi R, Martelli MF, Grignani F, Canino S, Minelli O, Ciani C, Mori A, Fagioli M (1987) Histopathology (in press).

    Google Scholar 

  24. Al Saati T, Gatter K, Gerdes J, Schwarting R, Caveriviere P, Rigal-Huguet F, Robert A, Stein H, Mason DY, Delsol G (1987) Am J Pathol (in press).

    Google Scholar 

  25. Kadin M, Nasu K, Sako D, Said J, Vonderheid E (1985) Am J Pathol 119:315–325.

    PubMed  CAS  Google Scholar 

  26. Ralfkiaer E, Stein H, Lange-Wantzin G, Thomsen K, Ralfkiaer N, Mason DY (1985) Am J Clin Pathol 84:587–593.

    PubMed  CAS  Google Scholar 

  27. Kaudewitz P, Stein H, Burg G, Mason DY, Braun-Falco O (1986) J Invest Dermatol 86:350–354.

    Article  PubMed  CAS  Google Scholar 

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© 1988 Springer-Verlag Berlin Heidelberg

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Stein, H., Dallenbach, F. (1988). Monoclonal Antibodies: Characterization and Diagnosis of Malignant Lymphomas and Other Skin Neoplasms. In: Orfanos, C.E., Stadler, R., Gollnick, H. (eds) Dermatology in Five Continents. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83360-1_3

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  • DOI: https://doi.org/10.1007/978-3-642-83360-1_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83362-5

  • Online ISBN: 978-3-642-83360-1

  • eBook Packages: Springer Book Archive

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