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The Orchestra of Mediators in the Pathogenesis of Septic Shock: A Review

  • Conference paper
Update 1991

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 14))

Abstract

Sepsis is a clinical syndrome that in most cases is induced by severe bacterial infections. Its manifestations may vary and include fever, leukocytosis, thrombocytopenia, tachycardia and tachypnea. Frequently, sepsis is complicated by the development of shock and multiple organ failure. Septic shock still continues to be a challenge for clinical investigators. In spite of advances in intensive care medicine and the availability of a large number of antibiotics, the mortality rate of this condition is still high, in some studies being 50–70%.

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Authors
  1. C. E. Hack
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  2. L. G. Thijs
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Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean Louis Vincent (Clinical Director) (Clinical Director)

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© 1991 Springer-Verlag Berlin, Heidelberg

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Hack, C.E., Thijs, L.G. (1991). The Orchestra of Mediators in the Pathogenesis of Septic Shock: A Review. In: Vincent, J.L. (eds) Update 1991. Update in Intensive Care and Emergency Medicine, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84423-2_27

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  • DOI: https://doi.org/10.1007/978-3-642-84423-2_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53672-7

  • Online ISBN: 978-3-642-84423-2

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