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Alterations in Gastrointestinal Barrier Function in Sepsis: The Effect of Lipopolysaccharide on Mucosal Permeability to Hydrophilic Solutes

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine 1992

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1992))

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Abstract

Structure and Function of Intestinal Intercellular Tight Junctions The epithelium of the gut serves as a barrier limiting the systemic absorption of intraluminal microbes and microbial products. It has been hypothesized, but certainly not proven conclusively, that derangements in the barrier function of the gut predispose critically ill patients to the development of bacteremia, fungemia, and/ or endotoxemia [1-3].

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Authors
  1. M. P. Fink
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Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Clinical Director) (Clinical Director)

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© 1992 Springer-Verlag Berlin Heidelberg

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Fink, M.P. (1992). Alterations in Gastrointestinal Barrier Function in Sepsis: The Effect of Lipopolysaccharide on Mucosal Permeability to Hydrophilic Solutes. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1992. Yearbook of Intensive Care and Emergency Medicine, vol 1992. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84734-9_24

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  • DOI: https://doi.org/10.1007/978-3-642-84734-9_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-55241-3

  • Online ISBN: 978-3-642-84734-9

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