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Current Evaluation of Pathologic Correlates of Dementia

  • Chapter
The Pathologic Physiology of Dementia

Part of the book series: Monographien aus dem Gesamtgebiete der Psychiatrie ((PSYCHIATRIE,volume 20))

Abstract

The involvement of pathology in mental disease was confirmed by Wilks in 1864:

The more marked changes which have been described as occurring in the insane, especially in those long demented, are those of an atrophic kind; the whole brain, when weighed, is found to be much lighter than an organ would be which had quite filled the skull case.

Thus on removing the dura mater, the surface of the brain is often quite hidden by the layer of serum which lies beneath the arachnoid, and filling up the spaces between the convolutions; instead of the sulci meeting they are widely separated, and their intervals filled with serum, and which, on being removed with the pia mater, the full depth of the sulci can be seen, At the same time the ventricles are distended by a large amount of serum; their walls are granular and the choroid plexus is full of cysts.

Such conditions are indicative of a wasted brain and are those which have been regarded as characteristic of a chronic form of insanity.

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  1. School of Medicine, Department of Pathology, Washington University, 660 South Euclid Avenue, St. Louis, MO, 63110, USA

    Professor Dr. Richard M. Torack

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  1. Professor Dr. Richard M. Torack
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© 1978 Springer-Verlag Berlin Heidelberg

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Torack, R.M. (1978). Current Evaluation of Pathologic Correlates of Dementia. In: The Pathologic Physiology of Dementia. Monographien aus dem Gesamtgebiete der Psychiatrie, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-88437-5_6

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  • DOI: https://doi.org/10.1007/978-3-642-88437-5_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-88439-9

  • Online ISBN: 978-3-642-88437-5

  • eBook Packages: Springer Book Archive

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